Full text is available at the source.
Abstract
Innate immunity is increasingly recognized as a major player in transplantation.
- Innate immunity contributes to inflammation during the early post-transplant phase.
- It influences how adaptive immune cells develop, potentially leading to either rejection or tolerance of the transplant.
- Recent findings suggest that innate allorecognition is linked to allograft rejection.
- The review discusses the physiology of innate immune components related to transplantation.
- Current and promising therapies include cellular treatments, anticomplement agents, and anticytokine strategies.
Simplified