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Intermittent Fasting Improves Glucose Tolerance and Promotes Adipose Tissue Remodeling in Male Mice Fed a High-Fat Diet
Intermittent fasting improves blood sugar control and changes fat tissue in male mice on a high-fat diet
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Abstract
Intermittent fasting decreased body weight and fat cell size in high-fat diet-fed mice.
- Intermittent fasting reduced energy intake in mice on both chow and high-fat diets.
- Fat mass was decreased and glucose tolerance improved in both diet groups after intermittent fasting.
- Mice on a high-fat diet showed reduced levels of macrophage markers in adipose tissue following intermittent fasting.
- Intermittent fasting altered genes related to inflammation in adipose tissue for both diet groups.
- In high-fat diet-fed mice, intermittent fasting decreased markers associated with fibrosis and increased matrix metallopeptidase 9 levels.
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