Association between Life’s Essential 8 and rheumatoid arthritis

Higher Life's Essential 8 (LE8) scores are associated with reduced odds of rheumatoid arthritis (odds ratio for each 10-point increase, 0.91).

• A population-based study analyzed data from 17,263 participants between 2007 and 2018.
• Higher scores in key components of LE8, such as sleep health and blood pressure, are linked to a lower risk of rheumatoid arthritis.
• A nonlinear association was found, indicating that the relationship between LE8 scores and rheumatoid arthritis is not strictly linear.
• The inverse relationship between LE8 scores and rheumatoid arthritis is stronger in young and female individuals.
• Results suggest that lifestyle factors defined by LE8 may help reduce the prevalence of rheumatoid arthritis.

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