Melatonin rhythms in renal transplant recipients with sleep–wake disturbances

A large proportion of renal transplant recipients had unexpectedly low salivary melatonin levels.

• Out of 29 renal transplant recipients, 18 had melatonin levels too low to calculate the dim-light melatonin onset (DLMO).
• Recipients with a measurable DLMO were significantly younger, with an average age of 46.4 years compared to 60.0 years in those without a measurable DLMO.
• Higher haemoglobin values were observed in recipients with a measurable DLMO (135.36 g/L) compared to those without (122.82 g/L).
• Recipients with a measurable DLMO reported less anxiety and had a better overall sense of coherence.
• These findings indicate potential health differences related to circadian rhythm stability among renal transplant recipients.

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