African health sciences

Small RNA molecules and the body’s biological clock: potential targets for diseases linked to disrupted daily rhythms

Updated

Abstract

MicroRNAs are important regulators of the circadian clock.

  • Circadian clocks coordinate behavior and physiology over a 24-hour period.
  • Molecular clocks rely on feedback loops that integrate various environmental and metabolic signals.
  • MicroRNAs are associated with the regulation of circadian rhythms in Drosophila and some small animal and human studies.
  • The review focuses on how microRNAs influence the expression of genes regulated by the circadian clock.

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