Journal of molecular biology

How microRNAs help control the body's internal clock

Circadian Biology Weekly Brief ↗PubMed ↗DOI ↗

Updated

Abstract

Circadian timekeeping mechanisms are present in virtually all living organisms to coordinate daily rhythms in physiology and behavior.

  • Circadian clock regulation involves complex interactions beyond simple feedback loops, including posttranscriptional, translational, and posttranslational mechanisms.
  • MicroRNAs (miRNAs) play a critical role in regulating various aspects of circadian clock function.
  • Research on miRNA-dependent regulation of the circadian timing system has been observed in multiple organisms, including flies, mammals, and higher plants.
  • Future research may focus on the role of miRNAs and noncoding RNAs in the circadian regulation of health and disease.

Simplified

Full Text

Full text is available at the source.
View Full Text ↗

Related papers

Feb '15
Interaction between microRNA and the body's daily biological clock
top 30% journal
cited by 23 papers
research support, non-u.s. gov't
Jan '18
New roles of microRNA in controlling the fruit fly’s daily biological clock
top 30% journal
cited by 34 papers
research support, n.i.h., extramural
Aug '21
Small RNA molecules and the body’s biological clock: potential targets for diseases linked to disrupted daily rhythms
cited by 8 papers
journal article
May '12
How microRNAs help control the daily biological clock in mammals
cited by 27 papers
research support, non-u.s. gov't
Mar '12
Renewing the Internal Body Clock Feedback Loop
top 1% journal
cited by 169 papers
research support, non-u.s. gov't
Nov '11
Earlier daily activity and restored internal body clock rhythms in mice with per2/dec gene mutations
cited by 8 papers
research support, non-u.s. gov't
Feb '13
Daily rhythms of urination and the possible role of the body’s internal clock
top 5% journal
cited by 77 papers
research support, non-u.s. gov't
Aug '09
MicroRNAs may help control the daily biological clock in fruit flies
cited by 170 papers
research support, n.i.h., extramural
Jul '11
How RNA controls the plant’s internal daily clock
top 2% journal
cited by 56 papers
research support, non-u.s. gov't
Mar '11
How RNA-level processes control daily biological clocks in complex cells
top 20% journal
cited by 14 papers
research support, non-u.s. gov't

What Lands in Your Inbox Each Week:

  • 📚7 fresh studies
  • 📝plain-language summaries
  • ✅direct links to original studies
  • 🏅top journal indicators
  • 📅weekly delivery
  • 🧘‍♂️always free

Recent issues from the circadian biology brief

issue #48
A blood test can now estimate your internal clock time using just 60 proteins
2 days ago7 studies
issue #47
Your body clock controls liver fibrosis — and scientists just found the on/off switch
1 week ago7 studies
issue #46
Night shift workers' metabolomes fall out of sync — and glucose pays the price
2 weeks ago7 studies
issue #45
80% of FDA-approved drug targets show clock-dependent activity — timing may be everything
3 weeks ago7 studies
issue #44
Sleeping late on weekends is independently linked to higher cardiovascular disease risk
4 weeks ago7 studies
issue #43
A smartphone app cut mood episode recurrence 3.4x in people with depression and bipolar disorder
5 weeks ago7 studies
issue #42
Morning cancer immunotherapy linked to 49% vs 40% disease control rate in 969 patients
6 weeks ago7 studies
issue #41
Timing cancer treatment before 3pm nearly doubled survival in lung cancer patients
7 weeks ago7 studies
issue #40
Male mice lived 12% longer when they ate only during an 8-hour window at night
8 weeks ago7 studies
issue #38
Emergency doctors had 67% higher odds of chronic pain when working evening shifts vs. morning shifts
10 weeks ago7 studies
explore the archive
See more issues from the circadian biology brief