The neuroarchitecture of the circadian clock in the brain of Drosophila melanogaster

Sep 11, 2003Microscopy research and technique

Brain network controlling daily rhythms in fruit flies

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Abstract

Specific neurons in the fruit fly's brain express clock genes that generate cell-autonomous molecular circadian oscillations.

  • Circadian rhythmic behavior in fruit flies is linked to the function of individual neurons that express specific clock genes.
  • Different groups of neurons contribute variably to the overall control of behavioral rhythms.
  • Connections between these neuronal clusters may influence how they synchronize with the external light-dark cycle.
  • Understanding these neuronal pathways could reveal how periodicity is imposed on behaviors like activity and pupal eclosion.

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