Obesity pillars

Nutrition advice for glucagon-like peptide treatments: Consensus from Asian Indian experts

Updated

Abstract

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and dual receptor agonists can lead to gastrointestinal adverse effects and nutritional deficiencies.

  • GLP-based therapies are associated with alterations in dietary intake.
  • Nutritional deficiencies resulting from these therapies may contribute to loss of muscle mass and bone density.
  • Structured nutritional support is necessary for individuals using GBTs, especially among Asian Indians.
  • The prevalence of sarcopenia in Asian Indians highlights the importance of tailored nutritional strategies.
  • Expert-driven recommendations were developed to prioritize nutritional needs for individuals with type 2 diabetes mellitus and/or obesity.

Simplified

Full Text

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Funding

Competing interests

The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Shashank R. Joshi reports grants or contracts from Abbott Healthcare Pvt Ltd; consulting fees from Marico, Franco Indian, Zydus Lifesciences, and TwinHealth; and support for attending meetings and/or travel from Abbott, Novo Nordisk, Sanofi, Eli Lilly, Lupin, Alkem, USV, Dr. Reddy’s Laboratories, UNS, and Cipla. Anoop Misra reports grants or contracts from Abbott Healthcare Pvt Ltd for the Delphi consensus preparation of this paper, as well as from USV (India), Eli Lilly, Novo Nordisk, Lupin, Cipla, and Zydus; honoraria for educational events from Abbott; and participation on a Data Safety Monitoring Board or Advisory Board. Ambrish Mithal reports grants or contracts from Abbott Healthcare Pvt Ltd; honoraria for educational events from Abbott; support for attending meetings and/or travel; and participation on a Data Safety Monitoring Board or Advisory Board. Banshi Saboo reports grants or contracts from Abbott Healthcare Pvt Ltd; honoraria for educational events from Abbott; and participation on a Data Safety Monitoring Board or Advisory Board. Krishna G. Seshadri reports grants or contracts from Abbott Healthcare Pvt Ltd; honoraria for educational events from Abbott; support for attending meetings and/or travel; and participation on a Data Safety Monitoring Board or Advisory Board. Subhankar Chowdhury reports grants or contracts from Abbott Healthcare Pvt Ltd; honoraria for educational events from Abbott; support for attending meetings and/or travel; and participation on a Data Safety Monitoring Board or Advisory Board. Ganapathi Bantwal reports grants or contracts from Abbott Healthcare Pvt Ltd; honoraria for educational events from Abbott; support for attending meetings and/or travel; and participation on a Data Safety Monitoring Board or Advisory Board. Bipin Sethi reports grants or contracts from Abbott Healthcare Pvt Ltd; honoraria for educational events from Abbott; support for attending meetings and/or travel; and participation on a Data Safety Monitoring Board or Advisory Board. Jothydev Kesavadev reports grants or contracts from Abbott Healthcare Pvt Ltd; honoraria for educational events from Abbott; speaker honoraria, consulting/advisory board fees, and funded research support from Abbott, Novo Nordisk, Eli Lilly, Medtronic, Roche, Sanofi, and Boehringer Ingelheim; participation on a Data Safety Monitoring Board or Advisory Board; an unpaid role as Editor-in-Chief of the International Journal of Diabetes and Technology; and unpaid leadership roles as Central Executive Committee Member of RSSDI and National President of the Diabetes Technology Trust of India. Arpan Dev Bhattacharya reports grants or contracts from Abbott Healthcare Pvt Ltd; honoraria for educational events from Abbott; support for attending meetings and/or travel; and participation on a Data Safety Monitoring Board or Advisory Board. Manash P. Baruah reports grants or contracts from Abbott Healthcare Pvt Ltd; honoraria for educational events from Abbott; research or educational grants from Abbott, Eli Lilly, Novo Nordisk, Sanofi, Eris, Mankind, Glenmark, Cipla, USV, and Sun Pharma; support for attending meetings and/or travel; and participation on a Data Safety Monitoring Board or Advisory Board. Ajay Budhwar reports grants or contracts from Abbott Healthcare Pvt Ltd; honoraria for educational events from Abbott; consultant and speaker fees and research/educational grants from Abbott and Novo Nordisk; support for attending meetings and/or travel; and participation on a Data Safety Monitoring Board or Advisory Board. Priti Thakor is an employee of Abbott Healthcare Pvt Ltd and reports grants or contracts from Abbott Healthcare Pvt Ltd and participation on a Data Safety Monitoring Board or Advisory Board. Sachin Shende is an employee of Abbott Healthcare Pvt Ltd and reports grants or contracts from Abbott Healthcare Pvt Ltd and participation on a Data Safety Monitoring Board or Advisory Board. Viswanathan Mohan reports grants or contracts from Abbott Healthcare Pvt Ltd; consulting fees; honoraria for educational events from Abbott; support for attending meetings and/or travel; participation on a Data Safety Monitoring Board or Advisory Board; and research or educational grants from Abbott, Medtronic, Novo Nordisk, Sanofi, Servier, Boehringer Ingelheim, Eli Lilly, Johnson & Johnson, Lifescan, Roche, MSD, Novartis, Aventis, Bayer, USV, Dr. Reddy’s Laboratories, Sun Pharma, Intas, Lupin, Glenmark, Zydus, IPCA, Torrent, Cipla, Biocon, Primus, Franco Indian, Wockhardt, Emcure, Mankind, Fourrts, Apex, GSK, and Alembic.
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