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Encoding seasonal information in a two‐oscillator model of the multi‐oscillator circadian clock
How a two-part internal clock keeps track of seasonal time
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Abstract
The suprachiasmatic nucleus (SCN) consists of about 10,000 neurons that function as individual circadian clocks.
- The diversity among SCN neurons allows for robust encoding of both daily light patterns and seasonal time.
- Synchronization among neurons simplifies their collective behavior to essentially two coordinated oscillators.
- A network of asymmetric repulsive-attractive coupling coordinates these oscillators.
- Physiologically relevant parameters influence the SCN network's behavior and its capacity to store information about seasonal changes in light exposure.
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