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Abstract
Polymer-based nanomedicines may offer innovative strategies to enhance treatment for glioblastoma multiforme (GBM).
- GBM presents significant challenges for diagnosis and treatment due to factors like the blood-brain barrier and tumor heterogeneity.
- Recent studies indicate that polymers and polypeptides could facilitate better penetration of the blood-brain barrier and tumor accumulation.
- The combination of chemotherapeutic agents with molecularly targeted treatments using polymers may enhance therapeutic effects.
- Multimodal therapies incorporating distinct treatment methods, such as phototherapy and immunotherapy, could be supported by polymer-based platforms.
- Preclinical validation of these polymer-based approaches shows promise in complex models, indicating potential for improved GBM therapies.
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