Neuroscience

New approaches and advances in glioblastoma treatment

Updated

Abstract

Nanotechnology may enhance treatment options for glioblastoma multiforme (GBM) by improving drug delivery mechanisms.

  • GBM is characterized by immune evasion, tumor repopulation by stem cells, and challenges with drug penetration across the blood-brain barrier.
  • Nanocarrier-based systems offer benefits such as improved biosafety, sustained drug release, and enhanced solubility.
  • Recent advancements in nanotechnology may help address the limitations of conventional and novel treatment modalities for GBM.
  • The review provides insights into the current landscape of GBM therapeutics, including updates on drugs and patents.
  • A critical evaluation of existing literature highlights both the therapeutic prospects and limitations of nanocarrier-based delivery strategies.

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Full Text

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Funding

Competing interests

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
PubMed

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