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Real-time imaging reveals spatiotemporal dynamics of cellular circadian clocks
Real-time imaging shows how cellular body clocks change over time and space
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Abstract
Circadian clocks have been localized to discrete sites within the nervous systems of several organisms, including mammals in the suprachiasmatic nucleus (SCN).
- The SCN contains multiple independent single-cell oscillators that contribute to circadian rhythms.
- New studies allow examination of these oscillators' activities over repeated cycles in tissue slices in vitro.
- Initial data highlight the role of intercellular membrane events in forming a reliable tissue pacemaker.
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