We can’t show the full text here under this license.
Abstract
Crohn's disease patients exhibited significantly reduced diversity in ileal compared to healthy controls.
- The study involved 32 Crohn's disease patients and 23 healthy controls, with most patients in remission.
- Crohn's disease patients showed differences in the composition of their ileal mucosa-associated microbiota compared to controls.
- A notable finding was the lower abundance of -producing bacteria in patients with a history of abdominal surgery.
- Butyric acid is important for intestinal health as it serves as a major energy source for intestinal cells.
- The reduction of butyric acid-producing bacteria may contribute to the pathophysiology of Crohn's disease by affecting the balance of microbial populations.
Simplified