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RETRACTED ARTICLE: Association of Life’s Essential 8 cardiovascular health with breast cancer incidence and mortality according to genetic susceptibility of breast cancer: a prospective cohort study
Links between heart health, breast cancer risk, and death based on genetic breast cancer risk
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Abstract
High cardiovascular health scores are associated with a 22% lower risk of breast cancer incidence and a 43% lower risk of breast cancer mortality among postmenopausal women.
- Among postmenopausal women, those with a high cardiovascular health score had a significantly decreased risk of breast cancer incidence and mortality compared to those with a low score.
- No significant association was found between cardiovascular health scores and breast cancer among premenopausal women.
- In high genetic risk groups, a high cardiovascular health score was linked to a 28% decrease in breast cancer incidence and a 71% decrease in mortality.
- No significant associations were observed in low genetic risk groups regarding cardiovascular health scores.
- Postmenopausal women with low cardiovascular health scores and high genetic risk showed a substantially increased risk of breast cancer incidence.
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Key numbers
22%
Decrease in breast cancer incidence risk
High score vs. low score among postmenopausal women
43%
Decrease in breast cancer mortality risk
High score vs. low score among postmenopausal women
6.26×
Increase in breast cancer incidence risk
Low score and high genetic risk vs. high score and low genetic risk