Neuron

Brain area receptors that influence alcohol drinking and craving

Updated

Abstract

Administration of liraglutide is associated with reduced alcohol intake in rodent models.

  • The study identifies a specific microcircuit in the lateral septum that involves GABAergic neurons.
  • Liraglutide activates GLP-1 receptor-expressing neurons in this circuit.
  • Inhibition of alcohol consumption was observed following systemic administration of liraglutide.

Simplified

Full Text

Full text is available at the source.

Funding

Competing interests

No competing financial interests reported.
PubMed

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