Exploring the Association of Sleep Profiles With Plasma Glycaemic Outcomes and 24‐h Interstitial Glucose Levels in Adults With Prediabetes: Findings From Chrono‐DM Study

Oct 14, 2025Journal of sleep research

Sleep patterns linked to blood sugar levels over 24 hours in adults with prediabetes

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Abstract

A total of 120 participants were categorized as morning (18.4%), intermediate (60.8%), or evening (20.8%) chronotypes.

  • Evening chronotypes showed a greater discrepancy in weekday-weekend awake time (0.7 h ± 1.1 h), indicating higher social jet lag.
  • Each additional hour of jet lag in awake time was associated with a 0.28 mmol/L reduction in 2-h postprandial glucose levels.
  • Longer sleep duration was positively associated with more time spent within the target glucose range (3.9-7.8 mmol/L).
  • Evening chronotype was associated with higher 24-hour mean glucose levels (0.65 mmol/L).
  • Evening chronotype and shorter sleep duration correlated with adverse glycaemic outcomes.

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Full Text

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