Temporal Orchestration of Immunity: How Circadian Clocks Coordinate Immune Responses

Nov 6, 2025Frontiers in bioscience (Landmark edition)

How Body Clocks Help Time and Coordinate Immune Responses

AI simplified

Abstract

The immune system exhibits robust circadian rhythmicity in functional organization.

  • Circadian regulation influences various immunological processes.
  • Pathogen-host interactions and immune cell behaviors may be modulated by circadian rhythms.
  • Light exposure and gut health are interconnected with immune function through circadian mechanisms.
  • The crosstalk between circadian oscillators and immune pathways could have clinical implications for immune-related diseases.
  • Chrono-immunotherapy is proposed as a strategy to improve treatment efficacy and reduce side effects by aligning therapies with circadian rhythms.

AI simplified

Full Text

Full text is available at the source.

what lands in your inbox each week:

  • 📚7 fresh studies
  • 📝plain-language summaries
  • direct links to original studies
  • 🏅top journal indicators
  • 📅weekly delivery
  • 🧘‍♂️always free