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Turning cold into hot: emerging strategies to fire up the tumor microenvironment
New ways to activate the tumor environment and boost its response
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Abstract
The tumor microenvironment (TME) is crucial in cancer progression and treatment strategies.
- The TME is a complex ecosystem that influences both primary and metastatic tumors.
- Dynamic features of the TME are essential for understanding cancer evolution.
- Cancer progression is affected by various systemic factors, including metabolism and the gut microbiome.
- 'Cold' tumors may be less responsive to treatment compared to 'hot' tumors.
- Strategies to convert 'cold' tumors into 'hot' ones could enhance therapeutic efficacy.
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