Latest Longevity & Aging Research Papers (Past Year) | Page 5

1 week ago • Frontiers in aging neuroscience

Using very fast MRI to estimate brain age in a clinic for thinking problemsUltra-fast MRI for brain-age prediction in a real-world cognitive disorders clinic

🎖️ Top 10% JournalFulltext (Open License)Article

1 week ago • ChemMedChem

Review of the Medicinal Chemistry of the NEET Protein FamilyMedicinal Chemistry Review of the NEET Protein Family

📖 Top 30% JournalArticle

1 week ago • bioRxiv : the preprint server for biology

Activating the protective renin-angiotensin system improves energy production and reduces stress in cells with Complex III deficiencyActivation of the protective arm of renin-angiotensin system enhances mitochondrial turnover improving respiration and decreasing integrated stress response in a human Complex III deficiency model.

Preprint

1 week ago • medRxiv : the preprint server for health sciences

FDA-Approved Tenofovir Alafenamide Treatment May Lower Biological Age in Healthy Adults by Targeting Mobile DNA ElementsAn FDA-Approved Tenofovir Alafenamide-Based Antiretroviral Therapy Reduces Biological Age in Healthy Adults: First Human Proof-of-Concept for Retrotransposon-Targeted Gerotherapeutics

Preprint

1 week ago • Cell chemical biology

A nature-inspired nanoparticle system for breaking down multiple proteins using the cell's recycling pathwayA nature-inspired nanoplatform for multi-protein targeted degradation via the autophagy-lysosome pathway

🥉 Top 5% JournalArticle

1 week ago • ACS chemical biology

Compounds that Boost Defective NPC1 Protein and Help Remove Cholesterol in Cells from Niemann-Pick Type C PatientsDiscovery of Autophagy Modulators that Increase I1061T NPC1 Expression and Promote Cholesterol Efflux in Niemann-Pick Type C Patient-Derived Fibroblasts

🎖️ Top 10% JournalArticle

1 week ago • medRxiv : the preprint server for health sciences

Using deep learning to predict health risks and death from the body's level of aging cellsA deep-learning based biomarker of systemic cellular senescence burden to predict mortality and health outcomes

Preprint

1 week ago • medRxiv : the preprint server for health sciences

Adjusting biological age measures for specific body areas in a long-living population using DNA methylationAging Out of the Blue: Region-Specific Epigenetic Clock Calibration for a Blue Zone with the DNAm SuperLearner

Preprint

1 week ago • Oncology research

Signs of Oxidative Stress in Bone Marrow Stem Cells from Untreated Advanced Breast CancerOxidative Stress Footprints in Bone Marrow Mesenchymal Stem Cells from Untreated Advanced Breast Cancer

📖 Top 20% JournalArticle

1 week ago • Biochemical and biophysical research communications

Resveratrol and nanodiamonds’ effects on cell protection and DNA damage in house cricketsEffects of resveratrol and nanodiamonds on sirtuin activity, oxidative stress and DNA damage in Acheta domesticus

📖 Top 30% JournalArticle

1 week ago • bioRxiv : the preprint server for biology

Problems in a new connection between cell cleanup and energy parts may contribute to cell recycling failure and brain damage in tau-related diseasesDysregulation of a novel autophagosome-mitochondria contact contributes to autophagy dysfunction and neurodegeneration in tauopathy

Preprint

1 week ago • Mitochondrion

Higher levels of miR-455-3p may increase removal of damaged mitochondria and support nerve and energy proteins in Alzheimer's diseaseOverexpression of miR-455-3p enhances mitophagy, synaptic and mitochondrial proteins in Alzheimer’s disease

📖 Top 20% JournalArticle

1 week ago • Nature aging

Using Space Travel as a Model for Faster AgingThe case for space as a model of accelerated aging

🥇 Top 1% JournalArticle

1 week ago • Vascular pharmacology

Metabolite analysis shows mTORC1 controls amino acid use in lymphatic vessel lining cellsUntargeted metabolomic profiling reveals mTORC1-dependent regulation of amino acid utilization in lymphatic endothelial cells

Article

1 week ago • bioRxiv : the preprint server for biology

Loss of a key cell cleanup process causes dry AMD-like eye damage in mice and can be improved by activating BK channelsLoss of Lamp2a-dependent chaperone-mediated autophagy drives dry AMD-like retinal pathology in mice and is rescued by BK channel activation

Preprint

1 week ago • Scientific reports

Interaction between inflammation and cell recycling in celiac disease organoidsCrosstalk between inflammation and autophagy in CeD organoids

📖 Top 20% JournalArticle

1 week ago • PloS one

Mitochondrial NAD kinase Pos5 is needed for making CoQ in yeastMitochondrial NAD kinase Pos5 is required for CoQ biosynthesis in yeasts

📖 Top 30% JournalFulltext (Open License)Article

1 week ago • Journal of molecular endocrinology

Cardiolipin may reduce insulin resistance by improving energy makers and boosting fat burningCardiolipin alleviates insulin resistance by ameliorating mitochondrial dysfunction and promoting fatty acid oxidation

Article

1 week ago • Current opinion in nephrology and hypertension

Stem cell therapy for kidney diseases: an updateMesenchymal/stromal cell therapy in kidney diseases: an update

📖 Top 20% JournalArticle

1 week ago • Cell death and differentiation

How PINK1 and STUB1 proteins control selective removal of peroxisomes by reducing PEX13PINK1 and STUB1 pathway orchestrates peroxisomal selective autophagy by PEX13 depletion

🥇 Top 1% JournalArticle

1 week ago • Women's health issues : official publication of the Jacobs Institute of Women's Health

Links Between Exercise, Immune Cell Aging, and Depression During PregnancyAssociations Among Physical Activity, Leukocyte Telomere Length, and Depression in Pregnancy: A Cohort Study

📖 Top 20% JournalArticle

1 week ago • Reviews in cardiovascular medicine

How Natural Aging Relates to New Cases and Changes Over Time in Irregular HeartbeatContributions of Biological Aging to Longitudinal Incidence and Dynamic Progression of Atrial Fibrillation: A Prospective Cohort Study

📖 Top 50% JournalFulltext (Open License)Article

1 week ago • Bioinformatics and biology insights

EpigeneticAgePipeline: A Tool for Measuring Biological Age Using DNA Methylation DataEpigeneticAgePipeline: An R Package for Comprehensive Assessment of Epigenetic Age Metrics From Methylation Microarrays

📖 Top 50% JournalArticle

1 week ago • Clinical neurology and neurosurgery

📖 Top 50% JournalArticle

1 week ago • Nature communications

Reducing lung blood pressure in mice by blocking a cell recycling process through the REV-ERBα/BNIP3 pathwayTargeting REV-ERBα/BNIP3 axis attenuates pulmonary arterial hypertension by repressing mitophagy in mice

🥈 Top 2% JournalArticle

1 week ago • Frontiers in endocrinology

Insulin's ability to increase sugar absorption is reduced in aging human fat cellsInsulin-stimulated glucose uptake is impaired in senescent human adipocytes

🎖️ Top 10% JournalFulltext (Open License)Article

1 week ago • Cell reports

Injecting lipid-free apolipoprotein A-I reduces inflammation by changing immune cell behaviorIntravenous injection of lipid-free apolipoprotein A-I dampens inflammation by reprogramming macrophage function

🥈 Top 2% JournalArticle

1 week ago • Dermatology and therapy

Combining Skin Treatments and Internal Care to Support Longer LifeIntegrative Dermatology for Longevity: The Synergy of Topical and Internal Approaches

🎖️ Top 10% JournalArticle

1 week ago • Pharmaceutical research

New Insights into How Withania somnifera Affects Inflammation and Aging SignalsNew Vistas for Withania somnifera in Signal Transduction of Inflammation and Aging

📖 Top 20% JournalArticle

1 week ago • Frontiers in public health

How pregnancy history and unhealthy lifestyle relate to faster biological agingAssociation of pregnancy history and unhealthy lifestyle with biological age acceleration: a large cross-sectional study

📖 Top 20% JournalFulltext (Open License)Article

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