Using Average Mid-Sleep Time to Estimate Internal Body Clock Phase

A single sleep-time assessment can represent melatonin phase by over 60%.

• Current methods for assessing circadian phase using melatonin are complex and time-consuming.
• Common sleep-time indices do not reliably reflect melatonin phase.
• The proposed single sleep-time assessment offers a simpler alternative for estimating circadian phase.
• This assessment improves the alignment of subjective sleep reports with objective melatonin phase measurements.

Simplified