Clinical cardiology

Better Heart and Kidney Protection with Tirzepatide Compared to Dulaglutide in Heart Failure with Preserved Pumping Function: A Large Real-World Study

Updated

Abstract

No direct head-to-head trials compare tirzepatide and dulaglutide in heart failure with preserved ejection fraction (HFpEF).

  • Tirzepatide is associated with superior weight loss compared to dulaglutide.
  • Recent trials, such as SURPASS-CVOT, suggest potential cardiovascular benefits of tirzepatide.
  • The lack of direct comparisons limits understanding of the relative effectiveness of these treatments in HFpEF.

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