Circadian clock-mediated regulation of blood pressure

Dec 5, 2017Free radical biology & medicine

How the body’s internal clock controls blood pressure

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Abstract

Circadian rhythms in blood pressure are influenced by peripheral clocks located in various organs.

  • Body functions, including blood pressure, vary over a 24-hour day due to circadian rhythms.
  • The central clock in the suprachiasmatic nucleus and peripheral clocks in organs regulate these rhythms.
  • Light and food cues help synchronize these clocks to the time of day.
  • Dysregulation of circadian blood pressure patterns is associated with an increased risk for cardiovascular disease.
  • Further research on the molecular clock mechanisms and diverse populations is needed to understand circadian regulation of blood pressure.

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