The diverse roles of the circadian clock in cancer

May 26, 2025Nature cancer

Different ways the body's internal clock may influence cancer

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Abstract

Circadian misalignment may affect a growing part of the human population and is linked to cancer.

  • Circadian rhythms regulate critical cellular processes such as immunity, metabolism, cell cycle control, and DNA repair.
  • There is divergent evidence regarding the specific roles of the circadian clock in various cancer types.
  • Circadian misalignment could be associated with early-onset cancers.
  • Understanding circadian regulation may aid in improving cancer prevention strategies.
  • Insights into the circadian clock may contribute to the development of chronomedicine-based therapies.

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