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Circadian Clock Control of Liver Metabolic Functions
How the Body's Internal Clock Controls Liver Metabolism
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Abstract
Genetic or environmental disruption of the circadian clock may cause metabolic diseases.
- The circadian clock regulates various metabolic functions in the gastrointestinal tract and liver.
- Disruption of the circadian clock can exacerbate existing pathological states.
- Asynchrony between external time and the circadian clock is increasingly common due to modern lifestyles.
- Interactions between altered energy metabolism and circadian disruption may lead to diabetes and other metabolic diseases.
- Circadian clock genes play significant roles in the regulation of glucose, lipid, and bile acid metabolism.
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