Glucagon-like peptide-1 drugs linked to poor bowel cleaning before colonoscopy in people with diabetes

Inadequate bowel preparation for colonoscopy may be associated with the use of glucagon-like peptide-1 receptor agonists (GLP-1RAs) in Japanese patients with diabetes.

• Glucagon-like peptide-1 receptor agonists are known to delay gastric emptying.
• Limited evidence exists regarding the effects of GLP-1RAs on bowel preparation specifically in Asian populations.
• The impact of different dosing frequencies (weekly versus daily formulations) on bowel preparation is not well understood.
• This examination focuses on the association between GLP-1RA use and bowel preparation adequacy.

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