Interactions between Gut Microbiota, Host Circadian Rhythms, and Metabolic Diseases

Mar 26, 2025Advances in nutrition (Bethesda, Md.)

How Gut Bacteria and Body Clock Interact in Metabolic Diseases

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Abstract

Circadian rhythms are associated with approximately 24-hour cycles influenced by both genetic and environmental factors.

  • Circadian rhythms synchronize biological processes to maintain metabolism and energy balance.
  • Disruptions to these rhythms are linked to metabolic disorders.
  • Microbial rhythms are affected by both the host's circadian clock and external factors like light and diet.
  • Changes in microbial communities and their functions can influence the host's metabolic processes.
  • There are bidirectional interactions between the circadian clock and microbiota that may impact lipid metabolism.

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