Higher Life’s Essential 8 score is associated with reduced risk of related surgery and all-cause mortality among 3232 individuals with inflammatory bowel disease in a longitudinal cohort study

Mar 12, 2025International journal of surgery (London, England)

Better Life's Essential 8 scores linked to lower risk of surgery and death in people with inflammatory bowel disease

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Abstract

Participants with a high (LE8) score had a 47% lower risk of -related surgery and all-cause mortality compared to those with a low LE8 score.

  • A total of 282 IBD-related surgeries and 259 deaths were recorded over a mean follow-up of 12.60 years.
  • In ulcerative colitis patients, a high LE8 score is associated with a decreased risk of IBD-related surgery and all-cause mortality.
  • The hazard ratios for ulcerative colitis patients with a high LE8 score were 0.47 for both IBD-related surgery and all-cause mortality.
  • No significant associations were found between LE8 score and adverse outcomes in Crohn's disease patients.

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Key numbers

0.47
Decrease in Surgery and Mortality Risk
Hazard ratio for -related surgery and all-cause mortality in UC patients.
3232
Study Population Size
Total number of participants with in the study.

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