Journal of sleep research

Timing of Melatonin Release at Home Linked to Treatment Follow-Through in Delayed Sleep Phase Disorder

Circadian Biology Weekly Brief ↗PubMed ↗DOI ↗

Updated

Abstract

Eighty-three percent of home dim light melatonin onsets (DLMOs) were not affected by light or sampling errors.

  • Thirty-two participants with delayed sleep phase disorder were assessed both at home and in a laboratory setting.
  • Most participants (66%) experienced light exposure greater than 50 lux during home assessments, but this occurred for only 1.5% of the assessment time.
  • Fifty-six percent of participants collected all saliva samples within 5 minutes of the scheduled times.
  • Home DLMOs occurred on average 10.2 minutes earlier than laboratory DLMOs.
  • A strong correlation was found between home DLMOs and laboratory DLMOs (r = 0.93, P < 0.001).

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