Physical exercise remodels visceral adipose tissue and mitochondrial lipid metabolism in rats fed a high‐fat diet

After 8 weeks, endurance training (ET) decreased body weight and visceral adiposity in rats fed a high-fat diet.

• Voluntary physical activity (VPA) decreased plasma glycerol levels and increased certain mitochondrial proteins in rats on a standard diet.
• Endurance training (ET) reduced plasma non-esterified fatty acids and glycerol levels in high-fat diet-fed rats.
• ET increased levels of proteins associated with fat transport and mitochondrial function in the visceral adipose tissue.
• ET led to a decrease in markers related to fat production in adipose tissue.
• The findings suggest that ET positively influences mitochondrial function and fat metabolism in obesity.

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