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Abstract
A phase 2a clinical trial evaluated the safety and preliminary efficacy of a single dose of intranasal 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) for alcohol use disorder.
- Participants and therapists described various psychological change processes related to treatment.
- The intervention included psychological support and structured cognitive behavioural therapy.
- Findings on safety and tolerability were assessed alongside psychological effects.
- Preliminary efficacy data may indicate potential benefits for relapse prevention in alcohol use disorder.
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