Shift work, gut dysbiosis, and circadian misalignment: The combined impact of nighttime light exposure, nutrients, and microbiota rhythmicity

Aug 7, 2025Chronobiology international

How Nighttime Light, Diet, and Gut Bacteria Rhythms Together Affect Shift Work and Body Clock Disruption

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Abstract

Circadian rhythm disruption is associated with a wide range of adverse health outcomes in shift workers.

  • Disruption of circadian rhythms may lead to metabolic, immune, cardiovascular, and neurobehavioral impairments.
  • Nighttime exposure to artificial light and irregular eating patterns could affect gut microbial composition and functions.
  • Circadian misalignment is linked to gut dysbiosis, inflammation, and metabolic dysfunction.
  • Emerging strategies such as chrononutrition and light modulation may help address these issues.
  • Targeted microbial interventions, like probiotics, are being explored as potential solutions.

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