The role of sleep disorders in cardiovascular diseases: Culprit or accomplice?

Jul 29, 2021Life sciences

Sleep disorders linked to heart and blood vessel diseases: cause or consequence?

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Abstract

Sleep disorders are frequently associated with cardiovascular diseases (CVDs).

  • Inflammation, sympathetic activation, and endothelial dysfunction are critical factors in both sleep disorders and CVDs.
  • There may be a bidirectional relationship between sleep disorders and CVDs, with high incidences observed in both conditions.
  • Novel potential mechanisms for the comorbidity include gut microbiota, orexin, and extracellular vesicles.
  • Understanding these mechanisms could inform future research and clinical strategies aimed at improving treatment outcomes for affected patients.

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