Latest Longevity & Aging Research Papers (Past Year) | Page 2

2 days ago • Biogerontology

Metformin may improve healthy aging by reducing frailty and protecting muscle and bone in middle-aged miceMetformin promotes healthspan by attenuating frailty and preserving musculoskeletal function–structure in middle-aged mice

📖 Top 20% JournalArticle

2 days ago • The international journal of biochemistry & cell biology

How Cell Recycling Controls Liver-Like Development of Human Fat-Derived Stem CellsAutophagy-mediated regulation of hepatic differentiation of human adipose tissue-derived mesenchymal stem cells

📖 Top 20% JournalArticle

2 days ago • Progress in neurobiology

Changes in Support Cells in Brain Aging: Different Cell Types and Area SensitivityGlial Dynamics in Brain Aging: Cellular Heterogeneity and Regional Vulnerability

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2 days ago • Neuroscience bulletin

Reducing Nerve Pain in Rats by Blocking a Specific Cell Recycling Process in the Spinal CordTargeting Fgr-STAT3 Mediated Autophagy Inhibition in the Spinal Cord Alleviates Neuropathic Pain in Rats

🎖️ Top 10% JournalArticle

2 days ago • Nature communications

Stress response may reduce PINK1-related removal of damaged mitochondria by maintaining their protein importThe integrated stress response suppresses PINK1-dependent mitophagy by preserving mitochondrial import efficiency

🥈 Top 2% JournalArticle

2 days ago • Scientific reports

📖 Top 20% JournalArticle

2 days ago • The Journal of cell biology

The SWR1 complex stops ATG proteins from being sent to the cell’s storage compartments by an unusual routeThe SWR1 complex prevents the vacuolar delivery of ATG proteins through a noncanonical pathway

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2 days ago • Ageing research reviews

🥈 Top 2% JournalArticle

2 days ago • Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

Removing aged cells does not slow disease progress in a mouse model of ALSElimination of senescent cells fails to attenuate disease progression in an ALS mouse model

📖 Top 30% JournalArticle

2 days ago • Military Medical Research

Biomarkers and treatments based on injury mechanisms for personalized care in multiple trauma with muscle and bone injuriesPathophysiology-guided biomarkers and therapeutics for precision trauma medicine in polytrauma with musculoskeletal injuries

🥈 Top 2% JournalArticle

2 days ago • Pharmacological research

Mitochondrial Quality Control as a Key Drug Target in AgingMitochondrial Quality Control as a Central Pharmacological Target in Aging

🥉 Top 5% JournalArticle

2 days ago • Biomacromolecules

Using Protein-Based Droplets to Deliver Rapamycin Inside Cells Targeting GRP78Intracellular GRP78-Directed Delivery of Rapamycin by Biomolecular Condensates of Hydra-Elastin-like Polypeptides

📖 Top 20% JournalArticle

2 days ago • Endocrine connections

How Stress Hormones and Cushing Syndrome May Connect to Cell Aging and Metabolic Aging”Glucocorticoids, Cushing syndrome and cellular senescence: a mechanistic link to metabolic ageing”

📖 Top 20% JournalArticle

2 days ago • Circulation research

Two Ways Cells Remove Damaged Mitochondria: Breaking Down and Releasing ThemTwo Routes for Removing Unhealthy Mitochondria: Degradation and Secretion

🥇 Top 1% JournalArticle

3 days ago • Frontiers in endocrinology

Cell aging and metabolism changes in type 2 diabetes: underlying processes and possible treatmentsCellular senescence and metabolic aging in type 2 diabetes: mechanistic insights and translational implications

🎖️ Top 10% JournalFulltext (Open License)Article

3 days ago • Drug design, development and therapy

mTOR Signaling Pathway’s Role in Antiphospholipid Syndrome and Possible Treatment TargetsmTOR Signaling Pathway in Antiphospholipid Syndrome: Pathogenesis and Potential Therapeutic Targets

📖 Top 20% JournalArticle

3 days ago • Differentiation; research in biological diversity

Targeting NNMT to treat scarring in the heart, liver, kidneys, and lungsNNMT as a therapeutic target in fibrosis: Insights from the heart, liver, kidneys, and lungs

📖 Top 30% JournalArticle

3 days ago • Aging

Faster biological aging linked to brain scans of aging and Alzheimer's diseaseAssociation of epigenetic age acceleration with MRI biomarkers of aging and Alzheimer’s disease neurodegeneration

📖 Top 20% JournalArticle

3 days ago • Cureus

Metformin's effects on cell energy and damage in age-related macular degenerationEffects of Metformin on Mitochondrial Health and Oxidative Stress in Age-Related Macular Degeneration: A Systematic Review

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3 days ago • Biochimica et biophysica acta. Molecular basis of disease

Using silibinin to activate GHSR-1α, boost mitochondrial cleanup, and protect kidney tubules in diabetic kidney diseaseTargeting GHSR-1α with silibinin to enhance mitophagy and prevent tubular injury in diabetic kidney disease

Article

3 days ago • Free radical biology & medicine

Transplanting Mitochondria Protects Eye Nerve Cells and Supports Nerve Repair in the Central Nervous SystemMitochondria Transplantation Preserves Retinal Ganglion Cells and Promotes CNS Axonal Regeneration

🥉 Top 5% JournalArticle

3 days ago • Journal of assisted reproduction and genetics

How mTOR signaling affects the health of mammalian egg cellsThe role of mTOR signaling in regulating the quality of mammalian oocytes

📖 Top 20% JournalArticle

3 days ago • Molecular cell

How species-specific cutting of the cell cleanup helper p62 influences responses to TNFSpecies-specific cleavage of the autophagy adaptor p62 dictates responses to TNF

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3 days ago • Acta pharmacologica Sinica

ADT-OH helps clear damaged mitochondria and reduces inflammation signaling in brain immune cellsADT-OH promotes mitophagy and suppresses the cytosolic mtDNA-cGAS-STING inflammatory cascade in microglia

🥉 Top 5% JournalArticle

3 days ago • Cell metabolism

Certain fats cause aging cells to die through iron-dependent cell damagePolyunsaturated lipids kill senescent cells by ferroptosis

🥇 Top 1% JournalArticle

4 days ago • Bone research

Mitochondrial DNA in bone surface cells may cause slower bone healing with agePeriosteal mitochondria DNA structures drive aging-associated poor skeletal repair

🥈 Top 2% JournalFulltext (Open License)Article

4 days ago • Journal of molecular medicine (Berlin, Germany)

Effects of short-term blue light exposure on the skin's internal clock and aging markers in skin cellsImpact of acute blue light irradiation on the molecular clock and markers associated with photoaging in skin cell models

🎖️ Top 10% JournalArticle

4 days ago • Molecular biomedicine

High-energy radiation reduces natural killer cells’ ability to clear aging intestinal cells in miceHigh-linear energy transfer radiation disrupts natural killer cell surveillance of senescent intestinal cells in the mouse intestine

🥉 Top 5% JournalFulltext (Open License)Article

4 days ago • Cureus

Overlap Between Alzheimer's Disease and Depression in Brain DegenerationThe Crossroads of Neurodegeneration: Exploring the Overlap Between Alzheimer's Disease and Depression

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4 days ago • Aging cell

Preserving NAD to Slow Cell Aging and Start Muscle and Bone RepairDouble‐Pronged NAD Preservation: Delaying Cellular Senescence and Initiating Musculoskeletal Regeneration

🥉 Top 5% JournalFulltext (Open License)Article

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