Nutrients

Chronodisruption: History and Progress of an 18-Year-Old Concept and How Time-Restricted Feeding in Mice May Protect Body Clocks and Metabolism During Long-Term Jetlag

Updated

Abstract

Time-restricted feeding in mice may prevent disruptions in peripheral circadian clocks during chronic jetlag.

  • Peripheral circadian clocks are linked to metabolic processes in the body.
  • Chronic jetlag can disrupt these clocks, potentially leading to metabolic issues.
  • Time-restricted feeding could help maintain the rhythm of these clocks despite jetlag.
  • The findings suggest that dietary timing may play a role in metabolic health during disruption of sleep patterns.

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Full Text

What this is

  • refers to the disruption of circadian rhythms, which can impact health.
  • This commentary discusses the concept's origins and developments over 18 years.
  • It reflects on a recent study about time-restricted feeding in mice and its effects on circadian clocks during chronic jetlag.

Essence

  • affects health by disrupting circadian rhythms. The commentary reviews its evolution and connects it to recent findings on time-restricted feeding.

Definitions

  • Chronodisruption: Disruption of biological rhythms, particularly circadian rhythms, affecting physiological processes and health.

Simplified

Funding

Competing interests

The authors declare no conflict of interest.
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