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Dorsal–lateral clock neurons modulate consolidation and maintenance of long‐term memory in Drosophila
Clock neurons in the side-top brain help form and keep long-term memory in fruit flies
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Abstract
Disruption of synaptic transmission in dorsal-lateral clock neurons (LNds) impaired long-term memory (LTM) maintenance.
- The circadian clock gene period (per) is crucial for the consolidation of long-term memory.
- Specific clock neurons, particularly LNds, are essential for maintaining long-term memory.
- Impairing LTM consolidation occurs when per RNA interference or a dominant-negative version of Per is induced in LNds.
- Transmitter release and Per function in LNds are associated with the processing of courtship memory.
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