The Yale journal of biology and medicine

How Time Supports the Immune System

Updated

Abstract

Nearly all organisms exhibit daily rhythms that are linked to immune function.

  • Circadian rhythms influence various physiological processes, including gene expression and behavior.
  • Several aspects of the immune response are regulated based on the time of day.
  • Recent studies indicate that disruptions in circadian rhythms may impair immune function.
  • Microbial components can affect the circadian clock, suggesting a bidirectional relationship.
  • Daily variations in immune responses have been observed in human subjects.

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