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Lysergic Acid Diethylamide and Psilocybin for the Management of Patients with Persistent Pain: a Potential Role?
Possible use of LSD and psilocybin to help manage long-lasting pain
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Abstract
Tentative evidence suggests that LSD (7 studies, 323 participants) and psilocybin (3 studies, 92 participants) may be beneficial for depression and anxiety in patients facing terminal illness.
- LSD and psilocybin are known to interact with certain receptors in the brain that influence pain perception.
- Both substances are associated with potential therapeutic effects for emotional distress in life-threatening conditions.
- Current safety profiles indicate that LSD and psilocybin can be safely administered under professional oversight.
- Further research is necessary to explore the effectiveness of these substances specifically for patients experiencing persistent pain.
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