Trending CRISPR Gene Editing Research Papers

4 days ago • Frontiers in oncology

Using CRISPR/Cas9 gene editing in cancer treatment: clinical applications, underlying methods, and future approachesCRISPR/Cas9 in cancer therapy: clinical translation, mechanistic strategies, and therapeutic directions.

📖 Top 20% JournalArticle

1 week ago • Nature biomedical engineering

Using gene editing inside the body to treat Huntington's diseaseIn vivo CRISPR base editing for treatment of Huntington's disease.

🥇 Top 1% JournalArticle

1 week ago • Blood

Prime editing allows drug-controlled T-cell therapies during immune suppressionPrime editing enables drug-controllable T-cell therapies with clinical immunosuppression.

🥇 Top 1% JournalArticle

4 days ago • Human gene therapy

Monkey Genomes Are Poor Models for Predicting Human CRISPR Off-Target EffectsNonhuman Primate Genomes Have Limited Relevance for Evaluating Human CRISPR Off-Target Effects.

📖 Top 20% JournalArticle

2 days ago • Biosensors & bioelectronics

DNA-guided step-by-step assembly of split RNA for activating CRISPR/Cas12aDIRECTOR: DNA-guided spatially ordered assembly of split crRNA for activating CRISPR/Cas12a.

🥉 Top 5% JournalArticle

4 days ago • The CRISPR journal

Improved method for making guide RNAs reduces immune response in lab testsAn Optimized Workflow for In Vitro Transcription of Single Guide RNAs Minimizes Innate Immune Activation.

🎖️ Top 10% JournalArticle

1 week ago • Bioinformatics (Oxford, England)

Deep learning design of guide RNA sequences without bases for precise CRISPR gene editingabCRISPR: deep learning-based design of abasic gRNA sequences for specific CRISPR-Cas genome editing.

🥉 Top 5% JournalArticle

1 week ago • International journal of biological sciences

Methods for delivering CRISPR gene editing treatments inside the bodyIn vivo delivery strategies for therapeutic CRISPR genome editing.

🥉 Top 5% JournalArticle

5 days ago • Molecular psychiatry

MicroRNA-148a influences depression-like behavior in mice through brain development and dopamine signalingMicroRNA-148a regulates depressive-like behaviors in mice via the Otx2/Dopaminergic signaling axis.

🥈 Top 2% JournalArticle

5 days ago • RSC advances

Using nanoporous gold electrodes with CRISPR to detect synthetic methylated DNA for breast cancer blood testsNanoporous gold electrode-assisted CRISPR/Cas12a electrochemical detection of synthetic methylated DNA models for breast cancer liquid-biopsy development.

📖 Top 30% JournalArticle

2 days ago • Analytical methods : advancing methods and applications

DNA-based system for combined detection of kanamycin antibiotic and bisphenol A chemicalHCR-assisted CRISPR/Cas12a platform enables logic-gate and multimodal detection of kanamycin and bisphenol A.

📖 Top 50% JournalArticle

2 days ago • The Analyst

A sensitive light-based sensor using enzyme-activated DNA and CRISPR for detecting sulfadimethoxineAn electrochemiluminescence biosensor for sulfadimethoxine detection based on enzymatic DNA walker-activated CRISPR/Cas12a cascade for signal enhancement.

📖 Top 50% JournalArticle

1 week ago • Cell reports

Neuronal activity screening links TMEM50A-related cell recycling to healthy synapses and long-term memoryA pooled CRISPR-based neuronal activity screen links TMEM50A-dependent MVB function to synaptic integrity and remote memory.

🥈 Top 2% JournalArticle

1 week ago • Transboundary and emerging diseases

Fast test using CRISPR for detecting Babesia parasites in ticks and livestock bloodA One-Pot RPA-CRISPR/Cas12a Assay for Rapid Genus-Level Detection of Babesia spp. in Ticks and Livestock Blood Samples.

📖 Top 20% JournalArticle

2 days ago • Marine biotechnology (New York, N.Y.)

A Reliable Method to Deliver Gene Editing Tools and Instructions into Fish EmbryosA Reproducible Electroporation Strategy for CRISPR-Cas9 RNP and mRNA Delivery in Fish Embryos.

Article

5 days ago • International immunopharmacology

Live CRISPR screening finds LTA4H may boost immunotherapy by affecting LTB4-driven neutrophil responseIn vivo CRISPR screening identifies LTA4H as a target for potentiating immunotherapy efficacy via the LTB4-neutrophil axis.

Article

6 days ago • Journal of fish diseases

A sensitive and easy-to-see test using CRISPR to detect Channel Catfish CalicivirusDevelopment of an RPA-CRISPR/Cas12a-Based Assay for Sensitive and Visual Detection of Channel Catfish Calicivirus (ChCV).

📖 Top 50% JournalArticle

4 days ago • bioRxiv : the preprint server for biology

CRISPR tests and humanized liver mice identify host factors for hepatitis B virusOrthogonal CRISPR screens and human liver chimeric mice identify hepatitis B virus host factors.

Preprint

4 days ago • Research square

Using Host Cell Guidance to Produce Human-Like Sugar Patterns in Komagataella phaffiiHost-Informed Engineering of Glycosylation in Komagataella phaffii for Human Biantennary N-Linked Glycans.

Preprint

1 week ago • bioRxiv : the preprint server for biology

Identifying essential genes in Streptococcus mutans and finding a working equivalent of the cell division regulator RocSDeciphering the Streptococcus mutans essentialome: multi-omic resolution of hypothetical genes and identification of a functional RocS equivalent.

Preprint