CRISPR Gene Editing Research Papers

3 weeks ago • Communications biology

Gene editing of European beech using a temporary cell-based system and CRISPR/Cas12aGenetic transformation and CRISPR/Cas12a-mediated gene editing of European beech (Fagus sylvatica L.) employing a transient protoplast system.

🥉 Top 5% JournalArticle

1 week ago • Microbial biotechnology

Highly Specific One-Step Test with Visual Result for Detecting Monkeypox Virus Clade IOne-Pot RPA-CRISPR/Cas12a Assay With Visual Readout for the Ultra-Specific Detection of Monkeypox Virus Clade I.

📖 Top 20% JournalEvaluation Study

2 weeks ago • Nature communications

A large-scale CRISPR screen to find factors that change how nerve cells respond to stimulationA massively parallel CRISPR-based screening platform for modifiers of neuronal depolarization.

🥈 Top 2% JournalResearch Support, N.I.H., Extramural

1 week ago • FEBS open bio

Removing IGF2 lowers but does not stop bone cancer growth in lab dishes and living modelsIGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo.

📖 Top 20% JournalFulltext (Open License)Article

3 weeks ago • Molecular therapy. Nucleic acids

Using double-stranded DNA and gene editing to fix cystic fibrosis mutations in human airway cellsDouble-stranded DNA donors and CRISPR-Cas9 for universal correction of mutations causing cystic fibrosis in human airway cells.

🥉 Top 5% JournalArticle

3 weeks ago • Cell genomics

Best settings for designing CRISPR-Cas9 gene interference librariesOptimized parameters for CRISPR-Cas9 interference library design.

🥇 Top 1% JournalArticle

3 weeks ago • Science advances

Creating pigs with increased mitochondrial DNA mutations and early aging using precise gene editingDevelopment of mitochondrial mutator pigs exhibiting increased mitochondrial DNA mutations and premature aging via prime editing.

🥈 Top 2% JournalArticle

3 weeks ago • Nature communications

Single-cell and live analyses show varied and organ-specific unintended effects and DNA rearrangements from CRISPR-Cas9Single-cell and in vivo profiling reveal heterogeneous and organ-specific CRISPR-Cas9 off-target and translocation outcomes.

🥈 Top 2% JournalArticle

3 days ago • Applied microbiology and biotechnology

A single-plasmid CRISPR-Cas9 system for genome editing in Bacillus bacteria that works without added inducersAn inducer-independent, single-plasmid CRISPR-Cas9 system for genome editing in Bacillus species.

📖 Top 20% JournalArticle

4 days ago • Biology

Goals, Public Views, and Uses of Genetically Modified and Gene-Edited OrganismsGenetically Modified and Gene-Edited Organisms-Objectives, Public Perception and Applications.

📖 Top 20% JournalArticle

4 days ago • International journal of molecular sciences

Using CRISPR to Create Melanoma Stem Cells That Are Vulnerable Without CD133Correction: Simbulan-Rosenthal et al. Employing CRISPR-Cas9 to Generate CD133 Synthetic Lethal Melanoma Stem Cells. Int. J. Mol. Sci. 2022, 23, 2333.

📖 Top 20% JournalPublished Erratum

4 days ago • Cells

Loss of VPS13B protein in cells causes stress in cell compartments, slower cell division, and formation of fibrous clumps linked to Cohen SyndromeModeling Cohen Syndrome in Phoenix Cells: VPS13B Loss Causes Organelle Stress, G1/S Delay, and Fibrillary Inclusion Bodies Formation.

🎖️ Top 10% JournalArticle

4 days ago • Biology

Using Fruit Fly Models to Find Natural Medicines: Shared Disease Signaling Paths and a Flexible Testing MethodDrosophila melanogaster Models for Natural Product Discovery: Cross-Disease Conserved Signaling Networks and a Generalizable Translational Pipeline.

📖 Top 20% JournalArticle

4 days ago • Plants (Basel, Switzerland)

Using CRISPR Gene Editing to Improve Solanaceae CropsGenome Editing in Solanaceae: Harnessing CRISPR-Cas Technology for Precision Crop Improvement.

📖 Top 20% JournalArticle

1 week ago • Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Improved Transformer-Based Tool for More Efficient DNA EditingEngineered Transformer Base Editor with Enhanced Editing Efficiency.

🥈 Top 2% JournalArticle

1 week ago • Nature communications

Highly sensitive detection of unintended CRISPR gene editing effects using Tracking-seq2Ultra-sensitive profiling of CRISPR-Cas off-target effects with Tracking-seq2.

🥈 Top 2% JournalArticle

1 week ago • Frontiers in plant science

Precise gene editing in plants using CRISPR-Cas: progress, uses, and future possibilitiesCRISPR-Cas technologies for precision genome editing in plants: advances, applications, and future perspectives.

📖 Top 20% JournalArticle

1 week ago • IUBMB life

Removing MMP9 lowers bladder cancer severity but does not improve treatment with BCG and anti-PD-L1 in a mouse modelMMP9 Knockout by CRISPR-Cas9 Reduces Bladder Cancer Malignancy But Does Not Synergize With BCG and Anti-PD-L1 in an Orthotopic Mouse Model.

📖 Top 20% JournalArticle

2 weeks ago • Physiologia plantarum

Creating a Gene-Editing Tool for Indica Rice and Finding a Gene That Controls Root GrowthEstablishment of a CRISPR-Cas9 Library for Indica Rice and Identification of OsOPR5 (LOC_Os06g11210) as a Regulator of Root Architecture.

📖 Top 20% JournalArticle

2 weeks ago • Aging cell

Base Editing Partly Improves Bone Problems in a Mouse Model of Hutchinson-Gilford ProgeriaIn Vivo Base Editing Partially Rescues Bone Dysplasia in a Mouse Model of Hutchinson-Gilford Progeria Syndrome.

🥉 Top 5% JournalArticle

2 weeks ago • Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Ultra-Sensitive HIV-1 Detection Using a Label-Free CRISPR Method on a SmartphoneAttomolar Detection of HIV-1 With Label-Free RCA-rCRISPR on Smartphone.

🥈 Top 2% JournalArticle

2 weeks ago • Frontiers in bioengineering and biotechnology

Using Modified Cell Particles to Deliver Gene Editing Tools for Targeted Immune TherapyEngineered MSC-exosomes as CRISPR-Cas9 delivery vectors for precision immunotherapy.

📖 Top 20% JournalArticle

3 weeks ago • ACS central science

A Two-Part Protein Helps Multiple eIF4A Molecules Bind RNA TogetherA Dimeric Protein-RNA Glue Promotes Multivalent eIF4A-RNA Assembly.

🥈 Top 2% JournalArticle

3 weeks ago • Frontiers in genome editing

Testing precise gene-editing enzymes on DNA wrapped in proteins using a measurement systemEvaluating high-fidelity CRISPR-Cas nucleases in nucleosomal contexts using a quantitative framework.

🎖️ Top 10% JournalArticle

3 weeks ago • Insects

Gene Editing of a Protein Involved in Starting Protein Production and Its Possible Role in Quick Cold Adaptation of Two Invasive Fruit FliesThe Gene Editing of Eukaryotic Translation Initiation Factor Binding Protein 3 and Its Potential Role in Rapid Cold Hardening of Two Invasive Fruit Flies.

📖 Top 30% JournalArticle

3 weeks ago • Molecules (Basel, Switzerland)

Using Light to Build and Break RNA-Protein Bonds to Control RNA Base EditingLight-Controlled Assembly and Disassembly of Covalent RNA-Protein Conjugates to Control RNA Base Editing.

📖 Top 20% JournalArticle

3 weeks ago • NAR cancer

SNHG family long RNAs help Ewing sarcoma cells grow by guiding small RNA changes in ribosomesSNHG family lncRNAs promote Ewing sarcoma cell fitness through intronic snoRNA-guided rRNA modifications.

🎖️ Top 10% JournalArticle

3 weeks ago • International journal of molecular sciences

Using AI to Compare Methods and Reveal Hidden Conflicts in CRISPR Guide RNA Prediction StudiesAI-Assisted Cross-Study Synthesis in Genome Editing: Comparing Long-Context Strategies and Uncovering Latent Contradictions in the CRISPR-Cas9 Guide RNA Prediction Literature.

📖 Top 20% JournalArticle

3 weeks ago • Cells

FHL3 Controls Changes in Blood Vessel Muscle Cells Through the MRTFB-SRF Signaling PathwayFHL3 Regulates Vascular Smooth Muscle Cell Phenotypic Switching Through the MRTFB-SRF Signaling Axis.

🎖️ Top 10% JournalArticle

3 weeks ago • Journal of fungi (Basel, Switzerland)

Creating an effective gene-editing method using CRISPR-Cas9 in the lichen fungus Umbilicaria muhlenbergiiEstablishment of an Efficient CRISPR-Cas9-Mediated Gene Disruption System in the Lichen-Forming Fungus Umbilicaria muhlenbergii.

📖 Top 20% JournalArticle

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