CRISPR Gene Editing Research Papers

1 week ago • Nature biomedical engineering

Using gene editing inside the body to treat Huntington's diseaseIn vivo CRISPR base editing for treatment of Huntington's disease.

🥇 Top 1% JournalArticle

3 weeks ago • Cell genomics

Using engineered virus-like particles together improves precise gene editing and large-scale testingCompound delivery of eVLPs enhances prime editing for targeted genome engineering and high-throughput screening.

🥇 Top 1% Journal

3 weeks ago • Immunity

Using CRISPR to quickly add large human antibody genes into mouse embryosCRISPR-mediated precise large fragment insertion in zygotes enables rapid generation of humanized immunoglobulin heavy-chain mice.

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1 week ago • Blood

Prime editing allows drug-controlled T-cell therapies during immune suppressionPrime editing enables drug-controllable T-cell therapies with clinical immunosuppression.

🥇 Top 1% JournalArticle

1 week ago • Horticulture research

Improving DNA base editing in potatoes by combining multiple optimizationsBoosting cytosine base editing in potato through synergistic optimization.

🥉 Top 5% Journal

2 weeks ago • Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Gene Editing to Treat Alzheimer's Disease by Changing APOE4 Using Prime Editor 7Therapeutic Gene Editing of APOE4 in Sporadic Alzheimer's Disease via Prime Editor 7.

🥈 Top 2% Journal

4 weeks ago • Nature genetics

Finding important lysine sites in mammal histone H3 using advanced CRISPR editingIdentifying critical lysines in mammalian histone H3 with high-throughput CRISPR prime editing.

🏆 Top 0.1% Journal

4 days ago • Frontiers in oncology

Using CRISPR/Cas9 gene editing in cancer treatment: clinical applications, underlying methods, and future approachesCRISPR/Cas9 in cancer therapy: clinical translation, mechanistic strategies, and therapeutic directions.

📖 Top 20% JournalArticle

1 week ago • The CRISPR journal

Changing Use Patterns of Advanced CRISPR Tools Shared by AddgeneThe Diversifying Distribution Trends of Maturing CRISPR Technologies by Addgene.

🎖️ Top 10% Journal

2 weeks ago • Med (New York, N.Y.)

Ethical issues in gene therapyEthics of gene therapy.

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2 weeks ago • Cell genomics

Using base editing for precise medical treatmentsBase editing for precision therapeutics.

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2 weeks ago • Molecular therapy : the journal of the American Society of Gene Therapy

Using base editors to precisely add and remove genes at the same time to create allo-CAR T cells with fewer DNA rearrangementsRepurposing base editors for targeted knock-in and simultaneous multiplex knockouts to generate allo-CAR T cells with minimal translocations.

🥈 Top 2% Journal

2 weeks ago • Molecular therapy : the journal of the American Society of Gene Therapy

Accurate liver gene editing of ASGR1 leads to strong and lasting cholesterol lowering without relying on LDL receptorsPrecise hepatic base editing of ASGR1 enables robust and durable LDLR-independent lipid lowering in vivo.

🥈 Top 2% Journal

2 weeks ago • Molecular therapy : the journal of the American Society of Gene Therapy

One Base Editing System for Multipurpose Genetic Engineering of Immune CellsA Singular Base Editing Platform for Polyfunctional Multiplex Engineering of Immune Cells.

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4 weeks ago • Science advances

Low ALDH6A1 levels change valine metabolism and may promote stomach cancer spreadReprogramming of valine metabolism mediated by abnormally low ALDH6A1 expression promotes invasive metastasis of gastric cancer.

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5 days ago • RSC advances

Using nanoporous gold electrodes with CRISPR to detect synthetic methylated DNA for breast cancer blood testsNanoporous gold electrode-assisted CRISPR/Cas12a electrochemical detection of synthetic methylated DNA models for breast cancer liquid-biopsy development.

📖 Top 30% JournalArticle

1 week ago • Bioinformatics (Oxford, England)

Deep learning design of guide RNA sequences without bases for precise CRISPR gene editingabCRISPR: deep learning-based design of abasic gRNA sequences for specific CRISPR-Cas genome editing.

🥉 Top 5% JournalArticle

1 week ago • Transboundary and emerging diseases

Fast test using CRISPR for detecting Babesia parasites in ticks and livestock bloodA One-Pot RPA-CRISPR/Cas12a Assay for Rapid Genus-Level Detection of Babesia spp. in Ticks and Livestock Blood Samples.

📖 Top 20% JournalArticle

1 week ago • Biomedicines

Gene Therapy for Beta-Globin Blood Disorders: From Molecular Fixes to Potential CuresGene Therapy for β-Haemoglobinopathies: From Molecular Correction to Curative Medicine.

📖 Top 20% JournalArticle

1 week ago • International journal of molecular sciences

Using CRISPR-Cas9 Gene Editing to Treat Inherited Liver DiseasesApplication of CRISPR-Cas9-Based Gene Editing Technology in Inherited Liver Diseases.

📖 Top 20% JournalArticle

1 week ago • Animals : an open access journal from MDPI

Biotech methods for making lab-grown poultry meat using stem cell reprogramming and gene editingBiotechnological Strategies for Cultured Poultry Meat Biofabrication Through Induced Pluripotent Stem Cell Reprogramming and CRISPR-Cas9-Mediated Genome Editing.

📖 Top 30% JournalArticle

1 week ago • Insects

How the Fruit Fly Helps Us Understand Human DiseaseCredit to the Fruit Fly: How the Tiny Insect Lights Up Our Understanding of Human Disease.

📖 Top 30% JournalArticle

1 week ago • Journal of fungi (Basel, Switzerland)

Fast CRISPR-based test for detecting grapevine black-foot disease pathogensA Rapid Recombinase Polymerase Amplification-CRISPR/Cas12a Assay for Detecting Grapevine Black-Foot Pathogens.

📖 Top 20% JournalArticle

1 week ago • Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Precise placement of split CRISPR activators improves sensitive detection of microRNA and classification of cancer cellsSystematic Position Mapping of Split CRISPR-Cas12a Activators Enables Highly Sensitive miRNA Detection and Cancer Cell Stratification.

🥈 Top 2% Journal

2 weeks ago • Frontiers in plant science

Using CRISPR-Cas to detect, monitor, and protect plants from virusesCRISPR-Cas systems for plant virus management: detection, surveillance, and host resistance.

📖 Top 20% Journal

2 weeks ago • Advanced science (Weinheim, Baden-Wurttemberg, Germany)

SOX5 May Drive Cancer Progression by Changing Gene Control in MYC-Driven B-Cell LymphomaSOX5 Orchestrates Malignant Evolution via Promoter-Centric Chromatin Remodeling in MYC-Driven B-Cell Lymphoma.

🥈 Top 2% Journal

2 weeks ago • Scientific reports

Using CRISPR to disable the white gene in the bluetongue virus carrier, Culicoides sonorensis biting midgesCRISPR-Cas9 mediated knockout of the white gene in the bluetongue virus vector, Culicoides sonorensis (biting midge).

📖 Top 20% Journal

3 weeks ago • International journal of molecular sciences

Tiny Engineered Tools for Gene Therapy: How They Work, Types, and Future PossibilitiesNanoengineering Systems for Gene Therapy: Mechanisms, Modalities, and Future Directions.

📖 Top 20% Journal

3 weeks ago • Plants (Basel, Switzerland)

AI-Guided Genome Editing Without DNA Insertion That Works for All Soybean Types to Improve CropsAI-Guided DNA-Free and Genotype-Independent Genome Editing for Soybean Improvement.

📖 Top 20% Journal

3 weeks ago • Cell death & disease

CRISPR screen finds DCAF4 helps liver cancer resist radiation by activating cell stress defenseCRISPR/Cas9 screen identifies DCAF4 as a novel protector of hepatocellular carcinoma against brachytherapy via stress granule-dependent NRF2 activation.

🥉 Top 5% Journal

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