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2 weeks ago • Frontiers in plant science

DNA-free genome editing methods for improving cropsGenome editing beyond transgenes: DNA-free technologies in crop improvement.

📖 Top 20% JournalArticle

2 weeks ago • Frontiers in immunology

CRISPR-Cas systems in Helicobacter pylori and gut bacteria as regulators of gut cancer riskThe emerging role of CRISPR-Cas systems in helicobacter pylori and the gut microbiota as regulators of gastrointestinal cancer risk.

🥉 Top 5% JournalArticle

2 weeks ago • Plant direct

Testing a flexible gene editing method called Free-BE in moss, maize, and wheatValidation of a Modular Base Editing Strategy, Free-BE, in Physcomitrium patens, Maize, and Wheat.

📖 Top 30% JournalArticle

2 weeks ago • Plants (Basel, Switzerland)

Recent Progress and Uses of Genome Editing for Precise Crop BreedingAdvances and Applications of Genome Editing in Precision Crop Breeding.

📖 Top 20% JournalArticle

2 weeks ago • Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Blocking COMPASS Promoter Activation Makes HDAC-Inhibited Gastric Cancer Keep Genes Turned Off During RecoveryDisabling COMPASS Promoter Licensing Shifts HDAC-Inhibited Gastric Cancer Toward Sustained Transcriptional Suppression During Recovery.

🥈 Top 2% JournalArticle

2 weeks ago • International journal of molecular sciences

Using Genetic and Molecular Methods to Enhance Pest Control Abilities of Insect-Killing NematodesAdvanced Genetic and Molecular Techniques for Improving Biocontrol Traits of Entomopathogenic Nematodes.

📖 Top 20% JournalArticle

2 weeks ago • Human mutation

Fast and Accurate Detection of USP26 Gene Variants Using CRISPR TechnologyRapid and Sensitive Detection of USP26 Cluster Variants Based on CRISPR/Cas12a.

🎖️ Top 10% JournalArticle

2 weeks ago • Frontiers in microbiology

Rapid visual test using omp25 and CRISPR technology to detect Brucella DNA linked to brucellosisDevelopment and preliminary validation of an omp25-based RPA-CRISPR/Cas12a visual assay for rapid screening of brucellosis-associated Brucella DNA.

📖 Top 20% JournalArticle

2 weeks ago • Frontiers in microbiology

Portable Tuberculosis Test Using a Paper Card and CRISPR Technology with Simple DNA AmplificationAn FTA card-based CRISPR/Cas12a platform with isothermal amplification for portable tuberculosis diagnosis.

📖 Top 20% JournalArticle

3 weeks ago • Frontiers in plant science

New developments in improving plant metabolism using synthetic biologyAdvances in plant metabolic engineering through synthetic biology.

📖 Top 20% JournalArticle

3 weeks ago • Cell proliferation

How DNA Packaging Changes Guide Repair Choices and Improve CRISPR Gene InsertionChromatin Modifications Orchestrate DNA Repair Pathway Choice: Epigenetics Strategies for Enhancing CRISPR-Cas9-Mediated Knock-In Efficiency.

🥉 Top 5% JournalArticle

3 weeks ago • Frontiers in genome editing

Using CRISPR tools that target both RNA and DNA to better reduce hepatitis B virus gene activityCombined RNA- and DNA-targeting CRISPR ribonucleoproteins enhance suppression of HBV transcripts.

🎖️ Top 10% JournalArticle

4 weeks ago • Nucleic acids research

Changes in the Lid Part of Cas12a Enzyme Affect Its Cutting to a Single DNA StrandSize and sequence variation of the Lid of the Cas12a nuclease domain results in a nickase phenotype.

🥇 Top 1% JournalArticle

1 month ago • Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Gene Roles in How Bacteroides thetaiotaomicron Uses Mucin for SurvivalDetermination of Gene-Level Fitness Contributions Across the Mucin-Utilization Network of Bacteroides thetaiotaomicron.

🥈 Top 2% JournalArticle

yesterday • Journal of hepatology

Liver biopsy shows accurate and effective correction of SERPINA1 gene by base editing in a patient with Alpha-1 Antitrypsin DeficiencyLiver biopsy confirms precise and efficient correction of SERPINA1 after in vivo Base Editing in a Patient with Alpha-1 Antitrypsin Deficiency.

🥇 Top 1% JournalCase Reports

1 week ago • Nature communications

A phage DUF669 protein helps fix DNA after cutting to resist host CRISPR defenseA phage DUF669 protein mediates post-cleavage DNA repair against host CRISPR immunity.

🥈 Top 2% JournalResearch Support, Non-U.S. Gov't

1 week ago • Genes

High-Precision Virus-Like Particles Carrying Cas12m for Changing DNA Bases from A to G and C to TEngineering of the High-Precision Cas12m Dual Base Editor-Loaded Virus-like Particles for A-to-G and C-to-T Conversions.

📖 Top 20% JournalArticle

3 weeks ago • MicrobiologyOpen

Combining two DNA techniques for highly sensitive detection of Mycoplasma bovisSynergistic Integration of Recombinase Polymerase Amplification and CRISPR-Cas12a Enables High-Sensitivity Detection of Mycoplasma bovis.

📖 Top 20% JournalArticle

2 weeks ago • Hemoglobin

Personalized Treatments for Sickle Cell Disease: From Biological Processes to Potential CuresPrecision Medicine in Sickle Cell Disease: From Molecular Pathways to Curative Strategies.

Article

yesterday • Journal of genetics and genomics = Yi chuan xue bao

Triggering death receptor 5 makes cancer cells more vulnerable to attack by natural killer and T cellsActivating death receptor 5 exposes a cancer cell vulnerability to natural killer and T cell attack.

🎖️ Top 10% JournalArticle

yesterday • STAR protocols

Method for detailed genetic analysis of editing results from nuclease, base, and prime techniques using CleanFinderProtocol for comprehensive genotyping of nuclease, base, and prime editing outcomes using CleanFinder.

📖 Top 20% JournalArticle

2 days ago • Talanta

Using a special protein and Cas12a to detect tetracycline with high sensitivityTranscription factor-regulated rolling circle transcription cascaded with Cas12a for sensitive determination of tetracycline.

📖 Top 20% JournalArticle

3 days ago • Biomaterials

Using targeted nanoparticles to deliver precise DNA editing for lung cancer treatmentTranscription activator-like effector base editing delivered by a targeted lipid nanoparticle for therapy of lung cancer.

🥉 Top 5% JournalArticle

4 days ago • Nature communications

Using Cas12a2’s self-destruct response for efficient and low-toxicity microbial genome editingRepurposing Cas12a2-mediated abortive infection for efficient and low-toxicity microbial genome editing.

🥈 Top 2% JournalArticle

4 days ago • Cell death and differentiation

DCST1 may cause cisplatin resistance in bladder cancer by stabilizing NFAT5 and blocking cell deathDCST1 drives cisplatin resistance via non-canonical ubiquitination and stabilization of NFAT5 to suppress PANoptosis in bladder cancer.

🥇 Top 1% JournalArticle

5 days ago • Nature structural & molecular biology

How the R2 Retrotransposon Works with CRISPR-Cas9 to Insert Genes in Specific PlacesStructural mechanism of programmable gene integration by the R2 retrotransposon coupled with CRISPR-Cas9.

🥇 Top 1% JournalArticle

5 days ago • Nature biotechnology

A smaller engineered Cas12m protein for activating multiple genes at once in living organismsAn engineered, compact Cas12m variant for multiplexed gene activation in vivo.

🏆 Top 0.1% JournalArticle

5 days ago • Nature plants

SmartPE allows precise gene editing in dicot crop plantsSmartPE enables efficient prime editing in dicot crops.

🥇 Top 1% JournalArticle

5 days ago • STAR protocols

Method for precise large DNA segment editing to create identical human stem cells using CRISPR-Cas9Protocol for precise large-region haplotype modification for isogenic human iPSC generation using CRISPR-Cas9.

📖 Top 20% JournalArticle

6 days ago • The Journal of experimental medicine

Cbfβ controls DNA folding to regulate different Il4 and Il13 gene activity in Th2 immune cellsCbfβ regulates DNA looping at the Il4-Il13 loci to control their differential expression in Th2 cells.

🥇 Top 1% JournalArticle

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CRISPR Gene Editing Research Papers