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3 weeks ago • Advanced science (Weinheim, Baden-Wurttemberg, Germany)

SiDT1 Controls Plant Shape Similar to Green Revolution Traits in Foxtail MilletSiDT1 Defines Plant Architecture Reminiscent of Green Revolution in Foxtail Millet.

🥈 Top 2% Journal

3 weeks ago • Cells

Using gene-silencing to lower TERT activity reduces growth of non-small-cell lung cancer cellsCRISPRi-Mediated Epigenetic Suppression of TERT Reduces Cell Growth in Non-Small-Cell Lung Cancer Cells.

🎖️ Top 10% Journal

3 weeks ago • Frontiers in microbiology

Improved gene editing methods for four common Gram-positive bacteriaAdvances in gene editing tools for four typical Gram-positive bacteria.

📖 Top 20% Journal

3 weeks ago • Applied microbiology and biotechnology

Selective gene editing in the cyanobacterium Cyanothece PCC 7425 using CRISPR/Cas12aTargeted genome editing of the non-model cyanobacterium Cyanothece PCC 7425 via CRISPR/Cas12a.

📖 Top 20% Journal

4 weeks ago • Bioinformatics (Oxford, England)

CROP: A context-aware method to predict CRISPR-Cas9 gene editing errors without relying on specific DNA featuresCROP: a feature-independent context-aware method for CRISPR-Cas9 frameshift prediction.

🥉 Top 5% Journal

4 weeks ago • eLife

Improved genome editing methods for precise DNA changes using prime editors in zebrafishOptimised genome editing for precise DNA insertion and substitution using prime editors in zebrafish.

🥈 Top 2% Journal

1 month ago • Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Fixing a Gene Improves Dopamine Cell Therapy in a Monkey Model of Parkinson's DiseaseGene Correction Enhances Dopaminergic Cell Therapy in a Nonhuman Primate Model of Parkinson's Disease.

🥈 Top 2% Journal

1 month ago • Scientific reports

A CRISPR-based fluorescent method to detect EGFR mutations in non-small cell lung cancerA "turn-on" CRISPR-mediated method using enhanced fluorescent bimetallic DNA nanoclusters for EGFR mutation detection in non-small cell lung cancer.

📖 Top 20% Journal

1 month ago • Journal of integrative plant biology

Creating watermelon that resists glyphosate using precise gene editingEngineering glyphosate-resistant watermelon by prime editing.

🥈 Top 2% Journal

4 days ago • Human gene therapy

Monkey Genomes Are Poor Models for Predicting Human CRISPR Off-Target EffectsNonhuman Primate Genomes Have Limited Relevance for Evaluating Human CRISPR Off-Target Effects.

📖 Top 20% JournalArticle

1 week ago • Mycoses

Rapid species-level detection of Trichophyton rubrum using gene editing and fluorescent test stripsA CRISPR-Cas12a and Quantum-Dot Lateral-Flow Assay for Rapid Species-Level Detection of Trichophyton rubrum.

📖 Top 20% JournalEvaluation Study

1 week ago • Analytica chimica acta

A new CRISPR-based digital test for detecting the CD44 proteinConstruction of the CRISPR/Cas12a-digital integrated immunoassay technology for CD44 detection.

📖 Top 20% JournalResearch Support, Non-U.S. Gov't

1 week ago • Current issues in molecular biology

Laboratory Tools and Data Analysis Methods Driving Advances in Clinical ResearchPipettes and Pipelines: The Weapons of Omics Sciences for a New Age of Clinical Studies.

📖 Top 30% JournalArticle

1 week ago • Current issues in molecular biology

Gene-Edited Stem Cells for Treating Blood Vessel Damage from Poor Blood Flow: Recent Progress and Future OutlookGene-Edited Stem Cells for Ischemic Vascular Disease: Current Advances and Future Perspectives.

📖 Top 30% JournalArticle

1 week ago • Genes

Errors in DNA Building Blocks Cause Unwanted Variation in Precise Gene EditingOligonucleotide Synthesis Errors Are a Source of Untoward Variation in HDR-Mediated Gene Editing.

📖 Top 20% JournalArticle

1 week ago • Human gene therapy

Comparing CRISPR-Cas9 Off-Target Prediction Tools Reveals Their Limits and Impact on Early TestingSystematic Benchmarking of CRISPR-Cas9 Off-Target Prediction Tools Reveals Limitations and Implications for Preclinical Assessment.

📖 Top 20% JournalArticle

2 weeks ago • Discover oncology

Using gene editing to understand and treat pancreatic ductal adenocarcinomaCRISPR guided gene knockout in pancreatic ductal adenocarcinoma molecular mechanisms and therapeutic strategies.

📖 Top 20% Journal

3 weeks ago • Polimery w medycynie

Biotech approaches to fight antibiotic resistanceBiotechnological strategies to combat antibiotic resistance.

📖 Top 50% Journal

2 days ago • Biosensors & bioelectronics

DNA-guided step-by-step assembly of split RNA for activating CRISPR/Cas12aDIRECTOR: DNA-guided spatially ordered assembly of split crRNA for activating CRISPR/Cas12a.

🥉 Top 5% JournalArticle

4 days ago • The CRISPR journal

Improved method for making guide RNAs reduces immune response in lab testsAn Optimized Workflow for In Vitro Transcription of Single Guide RNAs Minimizes Innate Immune Activation.

🎖️ Top 10% JournalArticle

5 days ago • Molecular psychiatry

MicroRNA-148a influences depression-like behavior in mice through brain development and dopamine signalingMicroRNA-148a regulates depressive-like behaviors in mice via the Otx2/Dopaminergic signaling axis.

🥈 Top 2% JournalArticle

6 days ago • Journal of fish diseases

A sensitive and easy-to-see test using CRISPR to detect Channel Catfish CalicivirusDevelopment of an RPA-CRISPR/Cas12a-Based Assay for Sensitive and Visual Detection of Channel Catfish Calicivirus (ChCV).

📖 Top 50% JournalArticle

1 week ago • Cell reports

Neuronal activity screening links TMEM50A-related cell recycling to healthy synapses and long-term memoryA pooled CRISPR-based neuronal activity screen links TMEM50A-dependent MVB function to synaptic integrity and remote memory.

🥈 Top 2% JournalArticle

1 week ago • International journal of biological sciences

Methods for delivering CRISPR gene editing treatments inside the bodyIn vivo delivery strategies for therapeutic CRISPR genome editing.

🥉 Top 5% JournalArticle

1 week ago • Nature communications

A molecular tool for precise genome repairMolecular velcro for precision genome repair.

🥈 Top 2% JournalArticle

1 week ago • The New phytologist

Precise replacement and removal of large DNA sections in rice using template-jumping prime editingEfficient homologous replacement and deletion of large genomic fragments through template-jumping prime editing in rice.

🥈 Top 2% JournalArticle

1 week ago • STAR protocols

Step-by-step method for editing yeast genes using CRISPR with PCR-made guidesProtocol for CRISPR genome editing in S. cerevisiae using PCR-based guide insertion.

📖 Top 20% JournalArticle

1 week ago • Analytical chemistry

DNA Nanowire-Enhanced CRISPR Test Using Three-Step Signal Boosting for Sensitive Detection of Myeloperoxidase ActivityDNA Nanowire-Assisted CRISPR/Cas12a Triple Cascade Amplification for Sensitive Detection of Myeloperoxidase Activity.

🎖️ Top 10% JournalArticle

1 week ago • Biosensors & bioelectronics

Using two-step DNA reactions and gene editing tools for clear electrochemical detection of the aflD gene and Aflatoxin B1Integration of dual-output TMSD and CRISPR/Cas12a for crosstalk-free electrochemiluminescence detection of aflD gene and AFB1.

🥉 Top 5% JournalArticle

1 week ago • Biosensors & bioelectronics

Detecting viral proteases using enzyme-triggered CRISPR/Cas activationProteolysis-triggered CRISPR/Cas activation via cascaded enzyme switches for viral protease detection.

🥉 Top 5% JournalArticle

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CRISPR Gene Editing Research Papers