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4 days ago • International journal of molecular sciences

Combined GLP-1RA and Low-Dose IL-2 Reduce Immune Activation and Brain Inflammation Signals in Living OrganismsCombination GLP-1RA and Low-Dose IL-2 Modulates Peripheral Immune Activation and Attenuates CNS Inflammatory Transcript Signatures In Vivo.

📖 Top 20% JournalArticle

4 days ago • International journal of molecular sciences

Metabolic Fatty Liver Disease: From Molecular Causes to Treatment ApproachesFrom Molecular Mechanisms to Clinical Strategies: A Comprehensive Overview of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD).

📖 Top 20% JournalArticle

4 days ago • Nephron

Metabolic and kidney effects of using liraglutide followed by setmelanotide in Bardet-Biedl Syndrome: a real-life case and reviewSequential liraglutide and setmelanotide therapy in Bardet-Biedl Syndrome: metabolic and renal outcomes in a real-world case report and literature review.

Case Reports

4 days ago • Hormones (Athens, Greece)

How receptors help control and treat type 2 diabetesAn illustrative summary of receptor-mediated mechanisms involved in the therapeutic regulation of type 2 diabetes.

📖 Top 30% JournalArticle

4 days ago • Biological psychiatry global open science

Drugs Targeting GLP-1 and GIP/GLP-1 Receptors for Alcohol Use, Obesity, and Heart-Related Metabolism ProblemsGLP-1 Receptor Agonist and GIP/GLP-1 Receptor Dual Agonist Therapeutics at the Intersection of Alcohol Use Disorder, Obesity, and Cardiometabolic Dysfunction.

🎖️ Top 10% JournalArticle

4 days ago • Metabolism: clinical and experimental

Avexitide’s effectiveness and safety for low blood sugar after weight-loss and other upper stomach surgeries: a phase 2b studyEfficacy and safety of avexitide for treatment of hypoglycemia following bariatric and other upper gastrointestinal surgeries: a phase 2b study.

🥈 Top 2% JournalArticle

4 days ago • Obesity research & clinical practice

Safety and effectiveness of liraglutide for treating obesity in Taiwanese teenagers: a real-world multicenter studyA multicenter real-world study on the safety and effectiveness of the glucagon-like peptide-1 receptor agonist (liraglutide) in adolescents with obesity in Taiwan.

📖 Top 20% JournalArticle

4 days ago • Medicine

Health outcomes linked to GLP-1 receptor agonist use in fatty liver disease with metabolism problems: A multinational studyClinical outcomes associated with GLP-1 receptor agonist use in metabolic dysfunction-associated steatohepatitis: A multinational cohort study.

📖 Top 50% JournalMulticenter Study

4 days ago • The Journal of clinical investigation

A specific brainstem circuit controls the unpleasant and appetite-reducing effects of GLP1R activatorsA single dorsal vagal complex circuit mediates the aversive and anorectic responses to GLP1R agonists.

🥈 Top 2% JournalArticle

4 days ago • North American Spine Society journal

Do drugs that activate GLP-1 receptors affect healing after neck bone fusion? A review and combined analysisDo glucagon-like peptide-1 receptor agonists influence cervical fusion outcomes? A systematic review and meta-analysis.

📖 Top 20% JournalArticle

5 days ago • Nature communications

Gene activity in human brain neurons that control energy balanceTranscriptome profiling of human hypothalamic agouti-related protein and proopiomelanocortin neurons regulating energy homeostasis.

🥈 Top 2% JournalArticle

5 days ago • American journal of physiology. Heart and circulatory physiology

Heart Effects of Long-Term GIPR and GLP-1R Activation in Lean and Obese Mice: Differences by Sex and DoseCardiovascular Effects of Chronic GIPR and GLP-1R Agonism in Lean and Diet-Induced Obese Mice: Sex Differences and Dose-Dependent Remodeling.

🎖️ Top 10% JournalArticle

5 days ago • Biomedical journal

Using Incretin-Based Treatments in Patient CareThe Incretin Revolution: Integrating Incretin-Based Therapies into Clinical Care.

📖 Top 20% JournalArticle

5 days ago • Annals of the New York Academy of Sciences

How Nearby Cell Signals in the Pancreas Affect Glucagon Release at Low, Normal, and High Blood Sugar LevelsIntra-Islet Paracrine Regulation of Glucagon Secretion During Hypoglycemia, Euglycemia, and Hyperglycemia.

Fulltext (Open License)Article

5 days ago • Diabetes/metabolism research and reviews

Low Levels of Active Thyroid Hormone Before Surgery, Especially in Women, Are Linked to Less Weight Loss and Diabetes Improvement After Bariatric Surgery in Adults with Normal Thyroid FunctionLow Preoperative Free Triiodothyronine, Particularly in Females, Is Associated With Reduced Weight Loss and Diabetes Remission After Bariatric Surgery in Euthyroid Adults.

🎖️ Top 10% JournalFulltext (Open License)Article

5 days ago • The Lancet regional health. Europe

Using incretin-based treatments as part of complete obesity careIntegrating incretin-based therapies into comprehensive obesity care: an EASO position statement.

🥈 Top 2% JournalArticle

5 days ago • Expert review of respiratory medicine

Links Between GLP-1 Therapy and Asthma Outcomes in People with ObesityAssociation of GLP-1-based therapy with asthma-related outcomes in patients with obesity: a propensity-matched retrospective cohort study.

Article

5 days ago • Diabetes, obesity & metabolism

Reducing Mealtime Insulin Using GLP-1 Medicines in Type 2 Diabetes Patients on Multiple Daily Insulin Shots: A Review of Clinical TrialsGLP-1 Receptor Agonist-Based Prandial Insulin De-Intensification in Outpatients With Type 2 Diabetes Receiving Basal-Bolus Insulin Therapy or Multiple Daily Injections: A Systematic Review and Meta-Analysis of Randomised Controlled Trials.

Article

5 days ago • Obesity pillars

Adjusting weight maintenance after hormone-related weight loss: new strategies beyond just continuing or stopping treatmentAdaptive maintenance after incretin-induced weight loss: Moving beyond the continue-or-stop paradigm.

📖 Top 20% JournalArticle

5 days ago • Obesity pillars

Differences by medical specialty in prescribing weight-loss drugs for obese teens in Saudi ArabiaSpecialty-based variation in glucagon-like Peptide-1 receptor agonist prescribing practices for adolescent obesity in Saudi Arabia.

📖 Top 20% JournalArticle

5 days ago • Diabetes, obesity & metabolism

Mental Health Safety of GLP-1 and Dual GIP/GLP-1 Treatments in Obese AdolescentsPsychiatric Safety of GLP-1 and Dual GIP/GLP-1 Receptor Agonists in Adolescents With Obesity.

Article

5 days ago • Problemy endokrinologii

Hair Loss During Obesity Treatment: Current Challenges and Possible Solutions[Hair loss during treatment of obesity: current state of the problem and potential solutions].

English Abstract

5 days ago • Clinical oral investigations

How sleep apnea and diabetes drugs affect mouth bacteria and oral healthObstructive sleep apnea, GLP-1 receptor agonist pharmacotherapy, and the oral microbiome: competing biological influences and implications for oral health monitoring.

📖 Top 20% JournalArticle

5 days ago • The American journal of medicine

Early heart and kidney outcomes after weight-loss surgery with prior use of GLP-1 receptor drugs or TirzepatidePrior GLP-1RA or Tirzepatide Use and Early Cardiorenal Outcomes After Metabolic and Bariatric Surgery.

📖 Top 20% JournalArticle

5 days ago • Experimental gerontology

GLP-1 receptor drugs, aging-related gene changes, and possible lifespan extension with medicineGLP-1 receptor agonists, epigenetic aging, and the prospect of pharmacological healthspan extension.

Article

6 days ago • Clinical obesity

Differences in Weight Loss and Influencing Factors of GLP-1 Receptor Agonists and Dual Agonists in People with Obesity: A Meta-AnalysisWeight Reduction Heterogenicity and Mediators of GLP-1RAs and Dual Agonists for Individuals With Obesity: A Meta-Analysis.

📖 Top 30% JournalMeta-Analysis

6 days ago • Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation

GLP-1 receptor drugs and their effects on body weight and heart healthEffects of GLP-1 receptor agonists on body weight and cardiovascular outcomes: a review.

📖 Top 30% JournalArticle

6 days ago • Cureus

How Tirzepatide and Semaglutide Compare in Effectiveness and Safety for Treating ObesityComparative Efficacy and Safety of Tirzepatide Versus Semaglutide for Obesity: A Systematic Review.

Article

6 days ago • Endocrine journal

Tirzepatide for high blood sugar caused by pasireotide in a hormone-producing pituitary tumor: a case report and reviewTirzepatide for pasireotide-induced hyperglycemia in a GH/TSH-producing pituitary adenoma/PitNET: a case report and literature review.

📖 Top 30% JournalArticle

6 days ago • Journal of pediatric endocrinology & metabolism : JPEM

Use of GLP-1 receptor drugs and mental health in teenagers with obesity: a look back studyGLP-1 receptor agonist use and mental health outcomes in adolescents with obesity: a retrospective review.

📖 Top 50% JournalArticle

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