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2 weeks ago • Nutrition (Burbank, Los Angeles County, Calif.)

Eating Habits as a Control System: From Gut-Brain Communication to Overall Body and Mind BalanceEating Hygiene as a regulatory system: from the gut-brain axis to biopsychosocial homeostasis.

2 weeks ago • Nutrition, metabolism, and cardiovascular diseases : NMCD

Heart disease outcomes linked to semaglutide and tirzepatide in type 2 diabetes and obesity: a comprehensive reviewCoronary artery disease -related outcomes associated with semaglutide and tirzepatide in type 2 diabetes mellitus and obesity: a systematic review and meta-analysis.

2 weeks ago • Nutrition, metabolism, and cardiovascular diseases : NMCD

Using semaglutide to manage heart disease in overweight and obese patients: expert adviceManagement of patients with cardiovascular disease and overweight/obesity: expert opinion on semaglutide use.

2 weeks ago • Current opinion in HIV and AIDS

New findings and treatment considerations for using glucagon-like peptide-1 drugs in older people with HIVGlucagon-like peptide-1 receptor agonists in the aging population of people with HIV: emerging evidence and clinical implications.

2 weeks ago • Cureus

Genetic Study Across Populations Links a Blood Sugar Regulator to Antipsychotic Drug Metabolic RisksMulti-ancestry Transcriptome-Wide Association Study (TWAS)-Informed Prioritization of Antipsychotic Metabolic Risk: Evaluation of GLP1R as a Shared Mechanistic Link.

2 weeks ago • Cureus

Urinary Problems Linked to Severe Obesity and How Weight Loss Surgery and Diabetes Drugs May Help Manage ThemUrological Complications of Morbid Obesity and the Role of Bariatric Surgery and Glucagon-Like Peptide-1 Receptor Agonists in Their Management: A Systematic Review.

3 weeks ago • Cureus

Cellulite as a Possible Sign of Metabolic Problems: Rethinking Body Changes with New Treatments Targeting Glucagon-Like Peptide-1Cellulite as a Possible Biomarker of Metabolic Dysfunction: Redefining Body Remodeling in the Glucagon-Like Peptide-1 Era Through the Cellulite Removal Medical Protocol-G21 Concept.

3 weeks ago • The Journal of endocrinology

Exendin-4 may improve high sugar damage to energy centers in insulin-producing cells through PKA/Drp1 signalsExendin-4 improves high glucose-induced mitochondrial dysfunction of pancreatic β-cells via PKA/Drp1 signaling.

3 weeks ago • Diabetes, obesity & metabolism

Effects of GLP-1 and Combined GIP/GLP-1 Drugs on Inflammation and Metabolism in Type 2 DiabetesEffects of GLP-1 Receptor Agonists and Dual GIP/GLP-1 Receptor Agonists on Inflammatory and Metabolic Biomarkers in Type 2 Diabetes: A Systematic Review and Meta-Analysis.

3 weeks ago • Diabetes, obesity & metabolism

Amylin-like Drugs as a New Major Option for Weight Loss: Review of Lab and Early Human StudiesAmylin Analogs: The Next Major Class of Weight Loss Therapy: A Review of Experimental Data and Early-Phase Clinical Trials.

3 weeks ago • Endocrine

Comparing IDegLira and insulin glargine in short-term intensive treatment for overweight or obese type 2 diabetes patientsComparative analysis of IDegLira versus insulin glargine in short-term intensive therapy for overweight or obese patients with type 2 diabetes mellitus.

3 weeks ago • Diabetes, obesity & metabolism

Safety of Tirzepatide in Everyday Medical Use Based on Reported Side EffectsSafety Profile of Tirzepatide in Real-World Clinical Practice: A Pharmacovigilance Study Using the FAERS Database.

3 weeks ago • Cureus

Sudden Small Intestine Blockage Linked to Tirzepatide (Mounjaro)Acute Small Bowel Obstruction Induced by Tirzepatide (Mounjaro).

3 weeks ago • Diabetes, obesity & metabolism

Kidney Problems Do Not Change How Zenagamtide Is Processed or Its Safety and TolerabilityRenal Impairment Does Not Affect Pharmacokinetics, Safety or Tolerability of Zenagamtide.

3 weeks ago • Acta diabetologica

Long-lasting blood sugar control with semaglutide treatment in an adult with latent autoimmune diabetes and multiple autoimmune conditions: a case report and reviewSustained metabolic control in latent autoimmune diabetes in adults (LADA) with semaglutide therapy in a patient with multiple autoimmune comorbidities: a case report and literature review.

3 weeks ago • Diabetes, obesity & metabolism

How Adults in Denmark Use Semaglutide for Weight Loss and What Effects They ExperienceTreatment Patterns and Experienced Effects of Semaglutide for Weight Management Among Adult Users in Denmark: A Community Pharmacy-Based Cross-Sectional Survey.

3 weeks ago • Pakistan journal of pharmaceutical sciences

Curcumin’s potential to affect the GLP-1 pathway through TGR5 in type 2 diabetes with obesityNetwork pharmacology combined with molecular docking to investigate the potential role of curcumin targeting TGR5 to modulate the GLP-1 pathway in T2DM with obesity.

3 weeks ago • Metabolism open

Glucagon-like Peptide-1 receptor agonists' direct effects on mitochondria in human cell models: A review and analysisDirect effects of glucagon-like Peptide-1 receptor agonists on mitochondrial function in human-derived in vitro models: A systematic review and meta-analysis.

3 weeks ago • Current medical research and opinion

Tirzepatide versus semaglutide for obesity in a Japanese subgroup from the global SURMOUNT-5 trialTirzepatide compared with semaglutide in obesity disease: a subpopulation analysis applying Japan Society for the Study of Obesity criteria in the global SURMOUNT-5 trial.

3 weeks ago • Pharmacoepidemiology and drug safety

Use of Negative Controls in Real-World Studies of Diabetes Drugs Acting on GLP-1 ReceptorsHow Negative Controls Are Used in Pharmacoepidemiology: A Methodological Scoping Review of Real-World Observational Studies of Glucagon-Like Peptide-1 Receptor Agonists.

3 weeks ago • NPJ cardiovascular health

Semaglutide's heart benefits relate more to the dose taken than to the amount of weight lostSemaglutide cardiovascular outcomes align more closely with attained dose than achieved weight loss.

3 weeks ago • Peptides

Glicentin as a weak activator of the glucose-dependent insulin-stimulating receptorIdentification of glicentin as a low-potency glucose-dependent insulinotropic polypeptide receptor agonist.

3 weeks ago • Diabetes, obesity & metabolism

How SGLT2 Inhibitors and GLP-1 Receptor Agonists May Affect Heart Rhythm Problems and Heart Events in Different DiseasesEfficacy and Safety of SGLT2 Inhibitors and GLP-1 Receptor Agonists on Ventricular Arrhythmias and Cardiovascular Events: A Disease-Stratified Network Meta-Analysis.

4 weeks ago • Diabetes, obesity & metabolism

Brain and Mental Health Effects of Tirzepatide, Semaglutide, and Similar GLP-1 TreatmentsNeuropsychiatric Outcomes With Tirzepatide, Semaglutide, and Other GLP-1 Receptor Agonists.

4 weeks ago • Diabetes, obesity & metabolism

Real-World Use of Semaglutide for Weight Loss: How Doses Are Adjusted, Stopped, and Linked to Weight ChangesReal-World Use of Semaglutide for Weight Management: Dose Titration, Discontinuation Patterns and Weight Changes.

4 weeks ago • The Journal of rheumatology

Influencing Metabolism and Inflammation in Psoriasis and Psoriatic Arthritis Using Diet, Diabetes Drugs, and Patient ViewsTargeting the Metabolic-Inflammatory Axis in Psoriasis and Psoriatic Arthritis: Evidence From Diet, Glucagon-like Peptide-1 Receptor Agonists, and Patient Perspectives.

1 month ago • Diabetes, obesity & metabolism

Weight Loss and Major Safety Risks Linked to GLP-1 Receptor Agonist Drugs: A Study Across Multiple CentersGLP-1 Receptor Agonists for Weight Loss and Risk of Major Safety Outcomes: A Multicentre Cohort Study.

1 month ago • Cureus

How Orforglipron compares to other GLP-1 receptor agonist drugsComparative Positioning of Orforglipron Among Selected GLP-1 Receptor Agonist Benchmarks: A Narrative Review.

1 month ago • Cureus

How Fructose and FTO Gene Differences May Influence the Effectiveness of Combined GLP-1 and GIP TreatmentsThe Effect of Fructose and FTO Gene Polymorphism on the Efficacy of GLP-1 and GIP Combination Therapies: A Narrative Review.

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GLP-1 Therapies Research Papers