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3 weeks ago • Molecular and cellular biochemistry

TRIM65 speeds up fatty cell buildup from blood vessel muscle cells and artery hardening by blocking mitochondrial cleaningTRIM65 accelerates VSMC-derived foam cell formation and arteriosclerosis progression by inhibiting mitophagy.

3 weeks ago • Journal of bioenergetics and biomembranes

The role of the mitochondrial sodium-calcium exchanger in brain cell agingThe role of mitochondrial Na⁺/Ca²⁺ exchanger in brain cell aging.

📖 Top 30% Journal

3 weeks ago • Molecular biology reports

Curcumin nanomicelle’s dose-dependent effects on cell recycling signals in rat testisDose-dependent effect of curcumin nanomicelle on autophagy signaling in testis; a study on normal Wistar rats.

📖 Top 30% Journal

3 weeks ago • Amino acids

L-citrulline’s effects on blood vessel health, artery stiffness, and heart metabolism during exercise in older and postmenopausal womenL-citrulline as a nitric oxide-modulating therapeutic adjunct to exercise: effects on vascular function, arterial stiffness, and cardiometabolic health in postmenopausal and older women.

📖 Top 30% Journal

3 weeks ago • Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Kaempferol May Reduce Knee Cartilage Damage in Spaceflight by Protecting Mitochondrial Health Through NOX4Kaempferol Attenuates Spaceflight-Associated Knee Cartilage Degradation by Targeting NOX4-Mediated Mitochondrial Dysfunction.

🥈 Top 2% Journal

3 weeks ago • Chinese medicine

New progress in electroacupuncture for memory and thinking problems around surgery: how it works and clinical proofAdvances in electroacupuncture for perioperative neurocognitive disorders: mechanisms and clinical evidence.

📖 Top 20% Journal

3 weeks ago • Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Frequent Sweetened Drink Intake Is Linked to Faster Biological Aging and Changes in Gut BacteriaFrequent Sweetened Beverage Consumption Is Associated With Accelerated Biological Aging: Evidence From a Population-Based Study and Gut Microbiota Analysis.

🥈 Top 2% Journal

3 weeks ago • Human gene therapy

Gene Therapy Using hBAG3 Improves Symptoms in a Mouse Model of Hereditary Muscle Disease Caused by Valosin ProteinAAV.hBAG3 Gene Therapy Improves Phenotype in a Valosin Containing Protein Mouse Model of Hereditary Inclusion Body Myositis.

📖 Top 20% Journal

3 weeks ago • Scientific reports

Thymoquinone's anti-inflammatory and antioxidant effects reduce early aging changes caused by D-galactose in miceAnti-inflammatory and anti-oxidative properties of thymoquinone attenuate D-galactose induced premature aging-associated alterations in mice.

📖 Top 20% Journal

3 weeks ago • PloS one

How problems in cell cleanup relate to nerve damage in diabetes, focusing on signaling and fat metabolismMolecular mechanisms of autophagy disorder in diabetic neuropathy: Focusing on signaling pathways and regulation of lipid metabolism.

📖 Top 30% Journal

3 weeks ago • Stem cells and development

How ATG5 Controls Stem Cell Flexibility to Maintain Function During Growth and IllnessATG5 Engineers Stem Cell Plasticity to Regulate Functional Fitness During Development and Disease.

3 weeks ago • Stem cell reviews and reports

How Mitochondrial Protein Tagging in Different Cell Types May Influence Stem Cell FateCell-Type-Specific Calibration of Mitochondrial Ubiquitination in Stem Cell Fate Decisions.

📖 Top 20% Journal

3 weeks ago • World journal of pediatric surgery

Loss of NAD+ metabolism linked to stopped skin lining growth in Hirschsprung diseaseNAD+ metabolic collapse and arrest of epithelial development in Hirschsprung disease.

📖 Top 50% Journal

3 weeks ago • Histology and histopathology

Henagliflozin may help kidney cells remove damaged mitochondria by activating energy sensors to slow diabetic kidney diseaseHenagliflozin promotes mitophagy in renal tubular cells by activating AMPK/ULK1 to alleviate the progression of diabetic kidney disease.

📖 Top 30% Journal

3 weeks ago • International immunopharmacology

Build-up of special DNA structures in brain immune cells is linked to changes in cell cleaning and worse damage after strokeMicroglial DNA G-quadruplex accumulation is associated with altered autophagy-related responses and aggravated ischemic brain injury.

3 weeks ago • Ageing research reviews

How Food Components Can Trigger or Protect Against Age-Related InflammationDietary Bioactive Compounds and Inflammaging: Pro-Inflammatory Triggers and Geroprotective Countermeasures.

🥈 Top 2% Journal

3 weeks ago • Scientific reports

Using genes to measure aging and improve care in gilthead sea bream farmingDecoding biological aging in Sparus aurata through a gene toolbox to infer welfare assessment and precision aquaculture interventions.

📖 Top 20% Journal

3 weeks ago • Molecular neurobiology

Small Protein Tagging in Mitochondrial Quality Control and Its Role in Brain Degeneration DiseasesSUMOylation in Mitochondrial Quality Control: Mechanisms and Implications for Neurodegenerative Disease.

🎖️ Top 10% Journal

3 weeks ago • Cellular signalling

NSUN2 links sugar and one-carbon metabolism to mTORC1 signaling controlled by Rag GTPasesNSUN2 integrates glucose and one‑carbon metabolism upstream of Rag GTPase-dependent mTORC1 signaling.

📖 Top 20% Journal

3 weeks ago • Life science alliance

Blocking CDK4/6 causes cells to release aging-related signals by slowing activation of NF-κBCDK4/6 inhibition induces a senescence-associated secretory phenotype via delayed NF-κB activation.

🎖️ Top 10% Journal

3 weeks ago • Neuro-degenerative diseases

Cell Cleanup Process in Alzheimer's Disease: How It Works, Current Treatments, and Future DirectionsAutophagy in Alzheimer's disease: mechanisms, clinical trials, and horizons.

📖 Top 20% Journal

4 weeks ago • Cell reports

A telomerase and SUCLG2 pathway may help drug-resistant persistent cells surviveA telomerase-SUCLG2 signaling axis drives drug resistance by protecting persister cells.

🥈 Top 2% Journal

4 weeks ago • Molecular and cellular biochemistry

High blood sugar causes aging in lining cells during dialysis, leading to scar tissue buildup by activating a key signaling pathwayMesothelial cell senescence induced by high glucose in peritoneal dialysis drives fibroblast activation and peritoneal fibrosis through KLF6-mediated activation of TGF-β pathway.

4 weeks ago • GeroScience

Removing or Changing Old Cells to Improve Skin HealthTargeting cellular senescence in dermatology: senolytic and senomorphic strategies.

🎖️ Top 10% Journal

4 weeks ago • Apoptosis : an international journal on programmed cell death

Mitochondria problems and cell aging may speed up pregnancy aging in early natural birthsMitochondrial dysfunction and cellular senescence drive accelerated gestational aging in spontaneous preterm birth: a narrative review.

🥉 Top 5% Journal

4 weeks ago • Naunyn-Schmiedeberg's archives of pharmacology

How fisetin may affect brain diseases by controlling inflammation, cell stress, and cell cleanup processesPharmacological mechanisms of fisetin in neurodegenerative disorders: regulation of neuroinflammatory, oxidative, and autophagic pathways.

📖 Top 30% Journal

4 weeks ago • Drug development research

Targeting Cell Recycling Processes in Alzheimer's Disease: The Role of Energy Control Pathways and Reusing Existing DrugsTargeting Autophagy in Alzheimer's Disease: Role of the AMPK/mTOR Pathway and Drug Repurposing.

📖 Top 30% Journal

4 weeks ago • JCI insight

Small blood vessel self-cleaning and cell death processes are key regulators of kidney scarring after blood flow injuryMicrovascular autophagy and caspase-3 activation are central regulators of renal fibrosis after ischemia-reperfusion.

🥉 Top 5% Journal

4 weeks ago • Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Breathable nanospray that responds to oxidative stress may help lung immune cells recover and reduce lung damage from radiationInhalable ROS-Responsive Nanospray Activates PPAR-γ to Restore Macrophage Mitochondrial Homeostasis and Attenuate Radiation-Induced Lung Injury.

🥈 Top 2% Journal

4 weeks ago • Autophagy

Low oxygen triggers a protein pathway that promotes cancer cell self-cleaning and spread in stomach cancerHypoxia-induced EPAS1/HIF2A-USP33-ATG101 axis drives oncogenic autophagy and peritoneal metastasis in gastric cancer.

🥈 Top 2% Journal

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