Latest Longevity & Aging Research Papers | Page 16 | OpenScience.ink

1 month ago • HEC forum : an interdisciplinary journal on hospitals' ethical and legal issues

Using Biological Age Scores and the Risk of Age Bias in Algorithms: An Ethics Guide for OrganizationsBiological-Age Scoring and the Risk of Algorithmic Age Discrimination: An Institutional Ethics Framework.

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1 month ago • Journal of the American Chemical Society

Newly Created Dual-Function Proteins for Targeted Protein BreakdownDe Novo-Designed Bifunctional Proteins for Targeted Protein Degradation.

🥇 Top 1% JournalArticle

1 month ago • European journal of pharmacology

New SIRT1 Activator F1462 May Reduce Blood Vessel Aging by Boosting Mitochondria through the SIRT1/PGC-1α/TFAM PathwayNovel SIRT1 up-regulator F1462 attenuates endothelial cell senescence and vascular aging by promoting mitochondrial biogenesis via activating the SIRT1/PGC-1α/TFAM pathway.

📖 Top 20% JournalArticle

1 month ago • Journal of endocrinological investigation

Lifelong untreated growth hormone deficiency does not change white blood cell telomere lengthLifelong congenital untreated isolated GH deficiency does not alter human leukocyte telomere length.

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1 month ago • Experimental & molecular medicine

Aging of blood-forming stem cells: gene activity and molecular changes with possible AI applicationsHematopoietic stem cell aging: a review of transcriptional and multi-omics insights and potential paths for AI integration.

🥈 Top 2% JournalArticle

1 month ago • Journal of advanced research

A cell aging pattern identifies COMP-positive support cells linked to CD8+ T-cell exclusion through a COMP-CD47 pathway in colorectal cancerTargeting a candidate stromal immune checkpoint: a cellular senescence signature identifies COMP⁺ cancer-associated fibroblasts associated with CD8⁺ T-cell exclusion via a predicted COMP-CD47 axis in colorectal cancer.

🥉 Top 5% JournalArticle

1 month ago • Cell proliferation

Macrophage Fat Balance May Contribute to Spinal Disc Degeneration by Reducing Clearance of Aging CellsMacrophage Lipid Homeostasis Drives IVDD via a Senescence-Dependent Impairment of Efferocytosis.

🥉 Top 5% JournalArticle

1 month ago • Life sciences

How Redox Signals Control Mitochondrial Quality by Linking Reactive Oxygen, Energy Molecules, and Calcium in DiseaseRedox-sensitive coordination of mitochondrial quality control: Integrating ROS, NAD+, and Ca2+ signaling in disease.

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1 month ago • Zhen ci yan jiu = Acupuncture research

Electroacupuncture’s effects on liver cell recycling in obese mice through energy and growth regulation pathways[Effect of electroacupuncture on hepatic autophagy in obese mice based on the AMPK/mTOR/ULK1 pathway].

English Abstract

1 month ago • The Biochemical journal

How different molecules control the mTORC1 pathway through cell surface receptorsSubstrate-specific regulation of the mTORC1 pathway by G protein-coupled receptors.

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1 month ago • Bio Systems

Aging as Increasing Blockages Across Key Processes: A Mathematical Model of Repair Limits, Cell Aging, Inflammation, and Failed RegenerationAging as cross-hallmark obstruction amplification: A sheaf-theoretic model of repair closure, senescence, inflammation, and regenerative failure.

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1 month ago • GeroScience

How Long-Term Obesity and Genetic Risk Are Linked to Aging in Older Chinese AdultsThe impact of cumulative obesity and genetic susceptibility on biological aging in Chinese older adults.

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1 month ago • Molecular neurobiology

Astrocyte Problems in Parkinson's Disease Linked to Reduced Cell Protection and Increased Cell Damage, Offering Targets for TreatmentDual-Pathway Astrocyte Failure in Parkinson's Disease: Therapeutic Targeting of Nrf2/TFEB Suppression and cGAS-STING/Ferroptosis Activation.

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1 month ago • Stem cell reviews and reports

Problems in the Brain's Blood Vessel and Support System in Diabetic Eye Disease: From Molecular Causes to Targeted TreatmentsDysfunction of the Neurovascular Unit in Diabetic Retinopathy: Advances from Molecular Mechanisms to Targeted Interventions.

📖 Top 20% JournalArticle

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