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3 weeks ago • Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

The C5a protein and its receptor may promote the shift from sudden to chronic kidney damage by increasing cell cleanup processesC5a/C5aR1 mediates AKI-CKD transition by enhancing autophagy.

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3 weeks ago • Trends in cancer

A new way cancer may use self-cleaning processes to weaken the immune responseA novel mechanism of autophagy-dependent immunosuppression in cancer?

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3 weeks ago • Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Liver damage caused by triptolide may involve inflammatory cell death triggered by NLRP3 and can be reduced by removal of damaged mitochondriaTriptolide-induced hepatotoxicity is mediated by NLRP3-dependent pyroptosis and inhibited by mitophagy.

3 weeks ago • Journal of gynecology obstetrics and human reproduction

Tuberous sclerosis complex and its effects on reproduction: an overviewTuberous sclerosis complex and reproduction: a scoping review.

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3 weeks ago • Molecular biology reports

Nicotinamide mononucleotide may improve heart cell metabolism damaged by high sugar and fat by stabilizing energy use through SIRT1Nicotinamide mononucleotide ameliorates high glucose/high fat-induced cardiomyocyte metabolic dysfunction through SIRT1-mediated CPT1A stabilization.

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3 weeks ago • Journal of medicinal chemistry

New synthetic molecules targeting cell aging in age-related lung scarringDiscovery of Novel Synthetic Cyclohexene-Based Small Molecules Targeting Senescence against Age-Related Pulmonary Fibrosis.

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3 weeks ago • International journal of molecular medicine

Hormone and metabolism imbalance may contribute to osteoarthritis: From joint changes to targeted treatmentsEndocrine‑metabolic imbalance drives osteoarthritis: From whole‑joint pathobiology to precision therapy (Review).

3 weeks ago • The Journal of nutrition

How Anthocyanins May Help Slow Aging: Processes and Future PossibilitiesAnthocyanins and Aging Intervention: Mechanisms and Prospects.

3 weeks ago • Free radical biology & medicine

Lack of ASAP3 reduces liver aging and is linked to longer healthy life in miceASAP3 deficiency alleviates hepatic senescence and correlates with extended healthspan in mice.

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3 weeks ago • Journal of translational medicine

Rapamycin treatment linked to changes in energy and inflammation processes and reduced fatigue in ME/CFS patients: early phase-II study resultsAssociation of rapamycin treatment with the modulation of purine metabolism, reduced microglial inflammatory responses, improved mitochondrial energy metabolism, and alleviation of fatigue symptoms in ME/CFS subjects: pilot findings from phase-II observational study.

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3 weeks ago • Nature medicine

Biological aging clocks linked to health and diseaseBiological aging clocks in health and disease.

3 weeks ago • GeroScience

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