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Associations of Cardiovascular Health and New-Onset Age-Related Macular Diseases From UK Biobank
Links Between Heart Health and New Age-Related Eye Diseases in UK Biobank Participants
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Abstract
During an average follow-up of 10.9 years, 7468 (2.8%) cases of (AMD) were documented.
- Individuals with moderate (CVH) had a 14% reduced risk of developing AMD compared to those with low CVH.
- Those with high CVH levels experienced a 23% reduction in AMD risk.
- A linear dose-response relationship exists between the cumulative Life's Essential 8 (LE8) score and AMD incidence.
- Achieving optimal CVH could potentially prevent 9.4% of AMD cases.
- Ideal blood glucose and blood pressure levels are associated with reductions of 3.3% and 8.7% in AMD cases, respectively.
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Key numbers
14%
Decrease in Risk with Moderate
Hazard ratio for moderate vs. low
23%
Decrease in Risk with High
Hazard ratio for high vs. low
9.4%
Potential Cases Prevented by Optimal
Population attributable risk percentage for achieving high