Circadian rhythms and the gut microbiota: from the metabolic syndrome to cancer

Oct 27, 2020Nature reviews. Endocrinology

How daily body clocks and gut bacteria are linked to metabolic syndrome and cancer

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Abstract

The metabolic syndrome accounts for the largest burden of non-communicable diseases worldwide.

  • Metabolic syndrome is linked to increased cancer risk.
  • Lifestyle factors contributing to metabolic syndrome can cause inflammation in intestinal microbiota.
  • Changes in intestinal microbiota structure and function may lead to metabolic syndrome and inflammation.
  • Circadian dysrhythmia is a common lifestyle factor associated with alterations in microbiome communities.
  • Disruption of circadian rhythms can affect metabolism, energy balance, and inflammation.

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