Oxytocin and its receptor in the process of parturition.

Jun 8, 2001Journal of the Society for Gynecologic Investigation

Oxytocin and its receptor in childbirth

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Abstract

The literature supports a significant role for the oxytocin/oxytocin receptor system in regulating human parturition.

  • Paracrine mechanisms may play a more critical role than endocrine mechanisms in parturition.
  • Regulation of the oxytocin receptor could be more influential than the presence of oxytocin itself.
  • A variety of chemical and physical factors, including sex steroids and uterine stretch, regulate the oxytocin/oxytocin receptor system.
  • There may be important interactions between the oxytocin system and the immune system.

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