Longevity & Aging Research Papers | Page 16 | OpenScience.ink

3 weeks ago • Nature

Abnormal activity of a brain cell receptor linked to Alzheimer's diseaseAberrant excitatory neuronal ERBB4 promotes Alzheimer's disease pathology.

Article

3 weeks ago • American journal of physiology. Cell physiology

NAD⁺ or β-Hydroxybutyrate May Protect Heart Cells from Fast Pacing Damage by Controlling Mitochondrial CleanupNAD⁺ or β-Hydroxybutyrate Each Protects Against Tachypacing-induced Metabolic Remodeling Through Regulation of Mitophagy in HL-1 Cardiomyocytes.

Article

3 weeks ago • Biochimica et biophysica acta. Molecular basis of disease

Rapamycin may reduce age-related changes and irregular heartbeat in the heart by improving metabolism controlled by HIF-1αRapamycin attenuates age-related atrial remodeling and fibrillation by targeting HIF-1α-mediated metabolic dysregulation.

Article

3 weeks ago • Journal of orthopaedic research : official publication of the Orthopaedic Research Society

Lanthionine Ketenamine Derivative May Improve Early Muscle Recovery After Blood Flow Injury by Regulating Cell Cleanup and StressLanthionine Ketenamine Derivative Enhances Early Functional Recovery Following Skeletal Muscle Ischemia-Reperfusion Injury Through Modulation of Autophagy and Oxidative Stress.

Article

3 weeks ago • Biochimica et biophysica acta. Molecular basis of disease

Mfn2-linked mitochondrial problems may cause kidney scarring by triggering cell death in chronic kidney diseaseMfn2-related mitochondrial dysfunction regulates renal fibrosis through ferroptosis in chronic kidney disease.

Article

3 weeks ago • International journal of general medicine

New Molecular Signs for Early Detection and Prevention of Age-Related Hearing LossPrecision Diagnostics in Age-Related Hearing Loss: Emerging Molecular Biomarkers for Early Detection and Targeted Prevention.

Article

3 weeks ago • Cureus

Nicotinamide Mononucleotide (NMN) May Prevent Age-Related Gene Changes Differently Across Tissues Through Protein Transport and Fatty Acid BreakdownNicotinamide Mononucleotide (NMN) Prevents Age-Associated Transcriptional Drift in a Tissue-Dependent Manner: Mechanistic Leads From Ras-Related Protein Rab-11A-Mediated Trafficking and Carnitine Palmitoyltransferase 2-Linked Fatty Acid Oxidation.

Article

3 weeks ago • Mechanisms of ageing and development

Body’s balance problems and internal clocks from a distance-based viewHomeostatic dysregulation and clocks: a distance-based perspective.

Article

3 weeks ago • Metabolism open

Gene activity and genetics point to EHHADH in a FUNDC1-linked mitochondrial system in diabetic kidney diseaseTranscriptomic and genetic evidence highlights EHHADH in a FUNDC1-associated mitochondrial network in diabetic nephropathy.

Article

4 weeks ago • Biochemical pharmacology

Changing the brain's innate immune memory in Alzheimer's disease: From immune cell activation to treatment resistanceImmunopharmacological reprogramming of innate immune memory in Alzheimer's disease: From microglial priming to therapeutic resilience.

Article

4 weeks ago • Mechanisms of ageing and development

DNA Methylation Clock Reveals Immune and Metabolic Aging Patterns Linked to MortalityEnsemble DNA methylation clock demonstrates Immune-metabolic aging signatures associated with mortality.

Article

4 weeks ago • Life sciences

Loss of bves causes heart pumping problems and heart muscle energy damage in zebrafishLoss of bves leads to cardiac contractile dysfunction and myocardial mitochondrial damage in zebrafish.

Article

4 weeks ago • Hematological oncology

Changes in Gene Control and Treatment Weaknesses That Vary by Situation in Blood Cell CancersEpigenetic Rewiring and Context-Dependent Therapeutic Vulnerabilities in Myeloproliferative Neoplasms.

Article

1 month ago • Life sciences

How Redox Signals Control Mitochondrial Quality by Linking Reactive Oxygen, Energy Molecules, and Calcium in DiseaseRedox-sensitive coordination of mitochondrial quality control: Integrating ROS, NAD+, and Ca2+ signaling in disease.

Article

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