Latest Longevity & Aging Research Papers

yesterday • Tissue & cell

Interaction between cell cleanup and inflammatory death in osteoporosis: Connecting energy control to bone inflammationAutophagy-pyroptosis crosstalk in osteoporosis: Linking mitochondrial homeostasis to inflammatory bone remodeling.

📖 Top 30% JournalArticle

yesterday • Herz

Can Age Be Changed to Lower Heart Disease Risk?Age: a modifiable risk factor for cardiovascular disease?

📖 Top 50% JournalArticle

yesterday • Autophagy

The role of cell-cleaning processes in oxidative stress and autoimmune thyroid inflammationMitophagy at the crossroads of oxidative stress and autoimmune thyroiditis.

🥈 Top 2% JournalArticle

yesterday • The journals of gerontology. Series A, Biological sciences and medical sciences

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yesterday • Cell

Fatty acid changes influence whether cells become old or die from iron-related damageFatty acid desaturation controls cellular fate decisions between senescence and ferroptosis.

🏆 Top 0.1% JournalArticle

yesterday • Cell biochemistry and function

Resveratrol may affect bone health by blocking inflammation through the SIRT1 pathway: molecular details and treatment possibilitiesResveratrol Modulates Bone Metabolism Through SIRT1-Mediated NF-κB Inhibition: Molecular Mechanisms and Therapeutic Implications.

📖 Top 30% JournalArticle

yesterday • Journal of controlled release : official journal of the Controlled Release Society

Testing cell aging as a treatment target in fatty liver disease linked to metabolism using navitoclaxValidation of senescence as a therapeutic target in metabolic dysfunction-associated steatohepatitis (MASH) through navitoclax delivery.

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yesterday • Aging cell

TOP2A Helps Keep Compact DNA Stable by Supporting LMNB1 to Prevent Cell AgingTOP2A Maintains Heterochromatin Stability by Sustaining LMNB1 Expression to Counteract Senescence.

🥉 Top 5% JournalArticle

yesterday • Advanced healthcare materials

Nanobody-Modified Outer Membrane Vesicles May Reduce Alzheimer’s-Like Brain Cell Damage by Changing Mitochondrial Cleanup and Inflammatory SignalsNanobody-Modified Outer Membrane Vesicles Attenuate Alzheimer's Disease-Like Neurodegeneration by Modulating Mitophagy-Associated Phenotypes and cGAS-STING-Related Inflammatory Signaling.

🥉 Top 5% JournalArticle

yesterday • Ageing research reviews

The Role of the Thioredoxin System in Cell Aging and Its Potential as a Treatment TargetThe Thioredoxin System in Cellular Senescence and Ageing: From Redox Homeostasis to Therapeutic Targeting.

🥈 Top 2% JournalArticle

2 days ago • Journal of Alzheimer's disease : JAD

Dry, but not wet, age-related macular degeneration is linked to higher Alzheimer's disease riskDry, but not wet, age-related macular degeneration increases Alzheimer's disease risk: Findings from a multidimensional analysis.

📖 Top 20% JournalArticle

2 days ago • Aging cell

A DNA Methylation-Based Predictor of Age Tested with Real and Random Missing DataA 209-Site DNA Methylation Predictor of Chronological Age Evaluated Under Empirical and Random Missingness.

🥉 Top 5% JournalArticle

2 days ago • Aging cell

Using Rodent Safety Data to Find Potential Longevity Agents That May Boost Mitochondrial HealthRepurposing Regulatory Rodent Toxicology Safety Archives to Identify Candidate Hormetic Longevity Agents Highlights Emergent Mitochondrial Mechanisms.

🥉 Top 5% JournalArticle

2 days ago • Journal of inflammation research

Mitochondrial Problems in Brain Diseases: Causes, New Findings, and Possible TreatmentsThe "Invisible Killer" of Neurodegeneration: Mitochondrial Dysfunction in Neurodegenerative Disorders, Mechanisms, Emerging Pathways and Therapeutic Strategies.

📖 Top 20% JournalArticle

2 days ago • Aging cell

Long-Term Culture of Human Skin Cells Mimics Aging and Allows Testing of Anti-Aging DrugsLong-Term Post-Mitotic Culture of Human Fibroblasts Recapitulates and Accelerates Features of In Vivo Aging and Enables Dynamic Testing of Anti-Aging Compounds.

🥉 Top 5% JournalArticle

2 days ago • Aging cell

Identifying Light-Based Signals Linked to Brain AgingEstablishing a Biophotonic Signature of Brain Ageing.

🥉 Top 5% JournalArticle

2 days ago • Journal of advanced research

Ziyu glycoside I may reduce aging and improve age-related decline by stabilizing an enzyme and restoring lactate productionZiyu glycoside I suppresses senescence and ameliorates age-related functional decline by stabilizing LDHA and restoring lactate output.

🥉 Top 5% JournalArticle

3 days ago • Current medical science

Using Lipid-Based Drugs to Target Aging Fat Cells for Treating Metabolic DiseasesIntervening in Adipocyte Senescence: Lipid Prodrugs as an Emerging Strategy for Metabolic Disease Treatment.

📖 Top 50% JournalArticle

3 days ago • Journal of visualized experiments : JoVE

Semi-Automated Analysis of Movement Health and Lifespan Using FlyTrDT in Fruit FliesSemi-Automated Integration of Motor Healthspan and Lifespan Analysis Using FlyTrDT Pipeline in Drosophila melanogaster.

📖 Top 50% JournalVideo-Audio Media

3 days ago • Journal of ethnopharmacology

Dendrobium officinale extract may improve Alzheimer's by affecting cell growth and recycling processesDendrobium officinale extract ameliorates Alzheimer's disease by modulating PI3K-AKT-mTOR pathway and autophagy-related processes: An integrated study combining feature-based molecular networking, network pharmacology and multi-omics.

📖 Top 20% JournalArticle

3 days ago • iScience

Genes linked to mitochondria cleanup that may help diagnose focal segmental glomerulosclerosisIdentification of mitophagy-related genes with diagnostic value in focal segmental glomerulosclerosis using bioinformatics analysis.

🎖️ Top 10% JournalArticle

3 days ago • Cardiovascular research

Energy metabolism decline caused by LncAAT is key to aging of blood vessel lining cellsLncAAT-mediated decline in energy metabolism is essential for vascular endothelial senescence in advancing age.

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3 days ago • Journal of orthopaedic translation

Changing immune cells in joint and muscle diseases: from local tissue roles to treatment possibilitiesMacrophage reprogramming in degenerative musculoskeletal diseases: From tissue-niche biology to therapeutic translation.

🎖️ Top 10% JournalArticle

3 days ago • The American journal of medicine

Current approaches to treating Alzheimer's diseaseCurrent development of therapeutic strategies for Alzheimer's disease.

📖 Top 20% JournalArticle

3 days ago • Experimental gerontology

Disrupted protein balance in aging muscles: Causes and possible treatments for muscle loss and weaknessProteostasis network dysregulation in aging skeletal muscle: Mechanisms and therapeutic targets in sarcopenia and muscle wasting.

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3 days ago • Experimental gerontology

Changes in 5hmC DNA Marks in Aging Beyond 5mCBeyond 5mC: 5hmC in the aging epigenome.

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3 days ago • GeroScience

Sesaminol reduces alcohol-related aging in the colon of middle-aged mice, possibly through protective cell pathwaysSesaminol attenuates alcohol-induced colonic senescence in middle-aged mice: potential involvement of the AhR-Nrf2 axis.

🎖️ Top 10% JournalArticle

3 days ago • Molecular biology reports

Cell aging in heart valve disease: is treatment to remove aged cells possible?Cellular senescence in calcific aortic valve disease: are we ready for senolytic therapy?

📖 Top 30% JournalArticle

3 days ago • Geriatric nursing (New York, N.Y.)

Understanding Long Life in Nursing: A Framework to Improve Healthy YearsConceptualizing longevity in nursing: a multidimensional framework for healthspan optimization.

📖 Top 20% JournalArticle

3 days ago • GeroScience

Irregular daily light cycles affect health but not lifespan in male miceChronic non-24-h light-dark cycles alter healthspan measures but not overall survival in male C57BL/6 J mice.

🎖️ Top 10% JournalArticle

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