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3 days ago • Progress in neurobiology

How Sex and Age Affect Brain Differences, Molecular Changes, and Treatment Response in StrokeThe Dimorphic Brain in Ischemic Stroke: How Sex and Age Shape Molecular Pathophysiology and Therapeutic Responsiveness.

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3 days ago • Free radical biology & medicine

β-Amyloid and Glutathione Imbalance Together Cause Fat Damage and Cell Death in Neuron-Like Cellsβ-Amyloid and glutathione dysregulation cooperatively drive lipid peroxidation and ferroptosis in neuron-like cells.

🥉 Top 5% JournalArticle

3 days ago • International reviews of immunology

Aging immune system decline and organ communication problems: Possible benefits of algae-based compounds and nutrition for healthy agingImmunosenescence and immune-organ axis dysfunction: Potential of algal bioactives and nutritional interventions for healthy ageing.

📖 Top 20% JournalArticle

3 days ago • The international journal of biochemistry & cell biology

New Insights into Calcium Signals and Cell Recycling ProcessesAdvances in calcium transients and autophagy.

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3 days ago • GeroScience

Increased activity of jumping DNA sequences distinguishes blood cell growth with DNMT3A mutations from those with TET2 mutationsRetrotransposable element derepression distinguishes DNMT3A-mutant from TET2-mutant clonal haematopoiesis.

🎖️ Top 10% JournalArticle

3 days ago • Autophagy reports

Complex interactions between the cell’s DNA-sensing system and its recycling processMultilayered interplay between the cGAS-STING pathway and autophagy.

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3 days ago • Reproductive sciences (Thousand Oaks, Calif.)

Autophagy's two roles in uterine scarring and how it relates to age-related fertility problemsDual Roles of Autophagy in Endometrial Fibrosis and Its Implications in Age-Related Reproductive Dysfunction.

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4 days ago • Fitoterapia

Huangqi Guizhi Wuwu decoction may reduce autoimmune nerve inflammation by helping cells clear damaged mitochondria and preventing brain immune cell deathHuangqi Guizhi Wuwu decoction suppresses experimental autoimmune encephalomyelitis by promoting PINK1/Parkin-mediated mitophagy and inhibiting microglial pyroptosis.

📖 Top 50% JournalArticle

4 days ago • The journal of nutrition, health & aging

Biological aging and blood fat markers linked to pancreatic diseases in UK Biobank participantsBiological aging, circulating lipid biomarkers and pancreatic diseases: a prospective cohort study based on the UK Biobank.

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4 days ago • Small science

A 3D Lab-Grown Human Muscle Model Showing Key Biological and Functional Signs of AgingA Biomimetic 3D Human Skeletal Muscle Microtissue for Modeling Biological and Functional Hallmarks of Aging.

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4 days ago • JID innovations : skin science from molecules to population health

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4 days ago • The Journal of clinical investigation

How LSD1 changes ATM to promote cell aging and organ declineLSD1-mediated demethylation of the DNA damage response factor ATM promotes senescence and organ aging.

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4 days ago • Journal of lipid research

Interaction between energy centers, cell packaging, and fat storage in fat metabolism changes in type 2 diabetesMitochondria-endoplasmic reticulum-lipid droplet crosstalk in lipid metabolic reprogramming in type 2 diabetes mellitus.

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4 days ago • Oral diseases

How Mouth Bacteria and Aging-Related Inflammation May Affect Gum Disease and Overall Health in Older AdultsThe Oral Microbiome-Inflammaging Axis in Elderly Periodontitis: Emerging Immunopathogenic and Systemic Mechanisms.

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4 days ago • Zhongguo zhen jiu = Chinese acupuncture & moxibustion

Moxibustion sensation may influence cell cleanup in the memory area of Alzheimer's model mice[Effect of moxibustion-induced deqi on hippocampal autophagy function in APPswe/PSEN1dE9 transgenic Alzheimer's disease mice].

English Abstract

4 days ago • Bioactive materials

How tiny cell particles can harm or help joint damage in osteoarthritis depending on the situationFrom pathogenic to reparative: Context-Dependent function of extracellular vesicles in osteoarthritis.

🥈 Top 2% JournalArticle

4 days ago • Research (Washington, D.C.)

Using Rapamycin-Releasing Nanofibers to Improve Lymphatic and Immune Response for Brain Covering Repair and Protection After Traumatic Brain Injury in RatsLymphatic-Immune Microenvironment Engineering via Rapamycin-Eluting Nanofibers for Meningeal Repair and Neuroprotection in Traumatic Brain Injury Rats.

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4 days ago • Obesity surgery

Weight Loss Surgery and Changes in the Heart-Based Biological Age Difference Over TimeMetabolic and Bariatric Surgery and Change in the AI-ECG-Derived Biological-Age Gap: A Longitudinal Cohort Study.

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4 days ago • Journal of feline medicine and surgery

Behavior, senses, and environment strategies to help cats age healthilyEXPRESS: Beyond the bowl: behavioural, sensory and environmental strategies to support healthy ageing in cats.

📖 Top 30% JournalArticle

4 days ago • Nature

RNF213 controls glycogen quality by directly tagging it for breakdownQuality control of glycogen through direct ubiquitylation by RNF213.

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4 days ago • European journal of human genetics : EJHG

Genetic and computer analysis of changes in telomere control genes in people with bone marrow failureGenomic and computational analysis of variants in telomere regulatory genes in subjects with bone marrow failure.

🎖️ Top 10% JournalArticle

4 days ago • Acta ophthalmologica

Faster biological aging is linked to a higher buildup of large drusenAccelerated biological ageing is associated with a large drusen burden.

🎖️ Top 10% JournalArticle

4 days ago • The Journal of arthroplasty

Faster Biological Aging Predicts Lower Function and Higher Surgery Risk in Knee ReplacementBiological Age Acceleration Predicts Functional Decline and Surgical Risk in Knee Arthroplasty.

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4 days ago • Molecular neurobiology

Non-coding RNAs and Mitochondrial Problems in Alzheimer's DiseaseNon-coding RNAs and Mitochondrial Dysfunction in Alzheimer's Disease: A Systematic Review.

🎖️ Top 10% JournalSystematic Review

4 days ago • GeroScience

Work Stress and Healthy Aging: A Framework for the Semmelweis Study and Workplace Health ProgramWork stress and healthy aging: A conceptual framework for the Semmelweis study and the Semmelweis-EUniWell workplace health promotion model program.

🎖️ Top 10% JournalArticle

4 days ago • The Journal of clinical investigation

UA-30 may improve movement problems by boosting targeted removal of damaged mitochondria in a mouse model of ALSUA-30 ameliorates motor deficits through RalA-mediated mitophagy in ALS mice.

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4 days ago • ACS biomaterials science & engineering

Complex Control Systems of Cell Aging: From How It Works to Diagnosis and TreatmentMultidimensional Regulatory Network of Cellular Senescence: From Mechanisms to Theranostics.

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4 days ago • Health science reports

How Different Biological Age Estimates May Predict Outcomes in Breast Cancer PatientsPrognostic Value of Different Biological Age Estimation Methods in Breast Cancer Patients: A Population-Based Cohort Study Using NHANES 1999-2020.

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4 days ago • iScience

The conflicting roles of DsbA-L in protecting against and contributing to stress responsesThe DsbA-L paradox in protective and pathogenic stress adaptation.

🎖️ Top 10% JournalArticle

4 days ago • International immunopharmacology

Radiation-caused irregular heartbeat linked to cell aging through the GATA4-NF-κB pathway and improved by D/Q cell-removal treatmentRadiation-induced atrial fibrillation is driven by cellular senescence via the GATA4 - NF-κB pathway and rescued by D/Q senolytic therapy.

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