Latest Longevity & Aging Research Papers | Page 2

3 days ago • Genes & diseases

The role of cell aging and possible treatments in spine disc breakdownThe role and potential therapeutic intervention of cellular senescence in intervertebral disc degeneration

🎖️ Top 10% JournalArticle

3 days ago • Journal of cellular and molecular medicine

How DAPK1 Inactivates Parkin to Increase Nerve Cell Damage by Triggering MITOL-Dependent BreakdownDAPK1 ‐Mediated Parkin Inactivation Enhances Neurotoxicity via MITOL ‐Dependent Degradation

📖 Top 20% JournalFulltext (Open License)Article

3 days ago • Journal of biochemical and molecular toxicology

Silymarin's protective role against lung damage caused by methotrexate through multiple molecular pathwaysAmeliorative Role of Silymarin in Methotrexate‐Induced Pulmonary Damage: A Multi‐Pathway Molecular Approach

📖 Top 30% JournalArticle

3 days ago • Frontiers in endocrinology

Rethinking the adrenal stress index by studying immune cell-linked resistance to stress hormonesBeyond adrenal fatigue: reframing the adrenal stress index through neutrophil-mediated glucocorticoid resistance

🎖️ Top 10% JournalFulltext (Open License)Article

3 days ago • Scientific data

Gene activity in colon cells of normal and Pink1-lacking miceA single-nucleus RNA-seq dataset of the colon in Pink1-deficient and wild-type mice

🎖️ Top 10% JournalArticle

3 days ago • Frontiers in molecular biosciences

Gene activity changes from chlorogenic acid and taurine treatment reveal how human skin cells ageTranscriptomic profiling of chlorogenic acid and taurine treatment in human skin cells provides insights into cellular senescence mechanisms

📖 Top 20% JournalFulltext (Open License)Article

3 days ago • Journal of Alzheimer's disease : JAD

Time-Restricted Eating and Its Potential in Alzheimer's Disease: A Research InvitationTime-restricted eating in Alzheimer's disease (TREAD): A call for research

📖 Top 20% JournalArticle

3 days ago • Autophagy

Phase separation of C19orf12 controls BNIP3 protein quality and supports mitochondrial cleanup in neuronsPhase separation of C19orf12 regulates BNIP3 protein quality control and maintains neuronal mitophagy

🥈 Top 2% JournalArticle

3 days ago • Nature communications

ASO therapy may reverse DNA damage, 3D genome structure problems, and cell aging caused by NOTCH2NLC GGC repeat expansionASO therapy rescues NOTCH2NLC GGC repeat expansion-induced genomic damage, 3D chromatin structural abnormalities, and senescence

🥈 Top 2% JournalArticle

3 days ago • Journal of Alzheimer's disease : JAD

Shared Genetic Factors Linked to Muscle Loss and Alzheimer's DiseaseUncovering polygenic and local genetic overlap between sarcopenia and Alzheimer's disease

📖 Top 20% JournalArticle

3 days ago • Orthopaedic surgery

Piezo 1’s role in disc degeneration: characteristics, causes, and possible treatmentsThe Role of Piezo 1 in the Study of Intervertebral Disc Degeneration: Phenotype, Mechanism and Treatment

📖 Top 30% JournalArticle

3 days ago • Biochemistry

Mitochondrial Ubiquitination as a Key Signal Balancing Mitochondrial Cleanup, Inflammation, and Cell DeathMitochondrial Ubiquitination as a Signaling Hub: Balancing Mitophagy, Inflammation, and Cell Death

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3 days ago • Journal of neural transmission (Vienna, Austria : 1996)

Genetic and environmental factors linked to ParkinsonismGenetic and environmental risk factors of Parkinsonism

📖 Top 20% JournalArticle

3 days ago • Journal of neurochemistry

L-Leucine boosts cell cleaning processes to reduce plaques in an Alzheimer's mouse modelL‐Leucine Upregulates Lysosomal Biogenesis and Autophagy to Lower Plaques in 5XFAD Mouse Model of Alzheimer's Disease

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3 days ago • Proceedings of the National Academy of Sciences of the United States of America

Microvesicle release may cause repeated breakdown of damaged heart cell parts and increased inflammation in sepsis-related heart problemsMicrovesicle release drives cycles of mitophagy flux disruption and inflammatory amplification in sepsis-induced myocardial dysfunction

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3 days ago • Acta biomaterialia

Smart delivery of engineered cell messengers carrying peptides to break down a-synucleinIntelligent delivery of autophagy-targeting chimeric peptides by engineered exosomes for the degradation of a-synuclein

🥉 Top 5% JournalArticle

4 days ago • Journal of lipid research

Watching fat breakdown in living mice using a special fluorescent reporterIn vivo visualization of lipophagy dynamics using the tfLiveDrop reporter mice

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4 days ago • Neuroscience letters

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4 days ago • Photodermatology, photoimmunology & photomedicine

How Mitochondrial Stress and Sunlight Together Affect Skin AgingInterplay of Skin Aging: Mitochondrial Stress and Ultraviolet Exposure

📖 Top 30% JournalArticle

4 days ago • Current protein & peptide science

Marine Compound CHNQD-00603 May Reverse Aging and Restore Bone-Building Ability in Stem Cells by Activating Cell Recycling PathwaysMarine-Derived Quinolinone CHNQD-00603 Triggers Autophagy via Suppressing the AKT/ERK/mTOR Pathway to Reverse Senescence and Restore Osteogenic Potential in Bone Marrow Mesenchymal Stem Cells

📖 Top 50% JournalArticle

4 days ago • Environmental pollution (Barking, Essex : 1987)

Nanoplastics worsen kidney damage in high blood pressure by promoting kidney aging and cell changes linked to lower Sirt1Nanoplastics Exacerbated Renal Injury amid Hypertension: Rethinking Health Hazards in Disease and Implication of Renal Senescence and EMT Associated with Sirt1 Downregulation

🥉 Top 5% JournalArticle

4 days ago • Biomaterials

Ceramic Materials That Support Tissue Repair and Reduce Cell AgingCeramic-based biomaterials: Combining regeneration with anti-senescence

🥉 Top 5% JournalArticle

4 days ago • Phytomedicine : international journal of phytotherapy and phytopharmacology

Myricetin helps protect liver cells by activating cell cleanup to improve fatty liver disease linked to metabolism problemsMyricetin stabilizes PINK1 to activate mitophagy and ameliorate metabolic dysfunction-associated steatotic liver disease

🎖️ Top 10% JournalArticle

4 days ago • Cell metabolism

Aging support cells in the brain’s emotion area may cause stress-related anxiety and high blood sugarAmygdala astrocyte senescence drives stress-induced anxiety and hyperglycemia

🥇 Top 1% JournalArticle

4 days ago • Journal of affective disorders

Faster biological aging linked to depression symptoms in US adults (2005-2018)Accelerated biological aging (GOLD BioAgeDiff) and depressive symptoms in US adults: NHANES 2005–2018

🥉 Top 5% JournalArticle

4 days ago • Ageing research reviews

How males and females respond differently to treatments that may extend lifespanSex differences in response to longevity interventions

🥈 Top 2% JournalArticle

4 days ago • Redox biology

How Changes in Energy-Producing Cell Parts May Contribute to Age-Related Macular DegenerationMitochondrial dynamics and their role in the pathogenesis of age-related macular degeneration: A comprehensive review

🥈 Top 2% JournalArticle

4 days ago • Ageing research reviews

Role of Nuclear Receptors in Age-Related Diseases and Potential TreatmentsNuclear receptors in age-related diseases: from mechanisms to drug discovery

🥈 Top 2% JournalArticle

4 days ago • Free radical biology & medicine

New Protein Changes in Cell Cleaning Processes and Their Links to Diabetes and Its ComplicationsThe Emerging Role of Novel PTMs in Autophagy: Implications for Diabetes and Its Complications

🥉 Top 5% JournalArticle

4 days ago • The Journal of reproduction and development

Father’s resveratrol intake linked to changes in energy units and chromosome tips in mouse embryos and offspringEffect of paternal resveratrol intake on mitochondria and telomere length in mouse embryos and offspring

📖 Top 30% JournalArticle

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